Evidence map›Paper›PMID 41940643›Full record

ArticlemBio2026

T cell responses to nonstructural proteins promote cross-serotype immunity to foot-and-mouth disease virus.

Suyu Mu, Shaobin Shang, Hu Dong, Shuang Wang, Lingbo Chen, Zhihui Zhang, Manyuan Bai, Zhidong Teng, Yaozhong Ding, Yun Zhang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Suyu Mu *State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.ORCID 0000-0001-6795-7710
Shaobin Shang *College of Veterinary Medicine, Institute of Comparative Medicine, Yangzhou University, Yangzhou, China.ORCID 0000-0003-4407-1911
Hu DongState Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.
Shuang WangState Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.
Lingbo ChenState Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.
Zhihui ZhangState Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.
Manyuan BaiState Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.
Zhidong TengState Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.
Yaozhong DingState Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.ORCID 0000-0003-3684-8217
Yun ZhangState Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.
Huichen GuoState Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.ORCID 0000-0003-0539-497X
Shiqi SunState Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.ORCID 0000-0003-4975-739X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T-cell responses play a pivotal role in protection against foot-and-mouth disease virus (FMDV), by enhancing neutralizing antibody (NAb) titers and shortening the duration of infection. To further elucidate the protective immune mechanisms mediated by T cells and develop novel candidate vaccines with cross-protective potential, multiple CD4 IMPORTANCE: CD4

Indexed as

Cross ProtectionFoot-and-Mouth DiseaseFoot-and-Mouth Disease VirusT-LymphocytesViral Nonstructural ProteinsAnimalsAntibodies, NeutralizingAntibodies, ViralCD40 LigandCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesEpitopes, T-LymphocyteSerogroupSwineSwine DiseasesViral VaccinesAntibodies, NeutralizingAntibodies, ViralCD40 LigandEpitopes, T-LymphocyteViral Nonstructural ProteinsViral VaccinesCD40Lcellular immune responsecross-protectionfoot-and-mouth disease virusT-cell epitope

Identifiers

PMID41940643
PMCPMC13170233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.