Evidence map›Paper›PMID 41940431›Full record

ReviewAnti-cancer agents in medicinal chemistry2026

Decoding the Anticancer Potential of Natural N-Heterocycles: Molecular Frameworks, Bioactivity, and Mechanistic Advances.

Honey Saini, Anuradha Mehra, Amit Mittal

Abstract readReview
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In one paragraph

Review in Anti-cancer agents in medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Honey SainiDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Lovely Professional University, Jalandhar-Delhi G.T. Road (NH-1), Phagwara (Punjab), 144411, India.
Anuradha MehraDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Lovely Professional University, Jalandhar-Delhi G.T. Road (NH-1), Phagwara (Punjab), 144411, India.ORCID 0000-0002-7405-8809
Amit MittalDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Lovely Professional University, Jalandhar-Delhi G.T. Road (NH-1), Phagwara (Punjab), 144411, India.ORCID 0000-0001-9689-1642

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is the leading cause of death and morbidity worldwide. Numerous scientists are trying to develop new anticancer medications that are more potent and less hazardous. This review, in contrast to previous reviews, focuses on the latest research findings from 2020-2025 on N-heterocyclic moieties as natural anticancer agents. This review provides a contemporary evaluation that integrates recent mechanistic discoveries, emerging nanotechnology-based delivery approaches, and translational progress relevant to natural Nheterocyclic anticancer agents. The literature was collected from online sources such as PubMed, Science Direct, Embase, and Google Scholar by searching with keywords like research paper on Natural N-heterocyclic products having anticancer activity, etc. The findings suggest that combining naturally obtained N-heterocyclic compounds with nanotechnology can provide us with a low-toxic anticancer drug in the future. The process of combining natural products containing N-Heterocyclic moieties with nanotechnology can be a game-changer for the development of anticancer medications. Still, there is a lot of research to be done in this area, which can change the viewpoint of the world regarding the treatment of cancer.

Indexed as

Antineoplastic AgentsBiological ProductsHeterocyclic CompoundsNeoplasmsAnimalsCell ProliferationDrug Screening Assays, AntitumorHumansMolecular StructureStructure-Activity RelationshipAntineoplastic AgentsBiological ProductsHeterocyclic Compoundsapoptosiscancercytotoxicmechanismnatural productN-heterocycle

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.