ArticleJournal of conservative dentistry and endodontics2026
An
Article in Journal of conservative dentistry and endodontics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: This study aimed to evaluate the mechanical and antibacterial properties of therapeutic seed extracts - chia, flax, guava, and papaya - in comparison to calcium hydroxide for potential intracanal application in endodontics. Methodology: A total of 150 extracted single-rooted teeth were cleaned, decoronated, and standardized to 12 mm. After biomechanical preparation, samples were sterilized and divided into two groups (A and B), each with five subgroups: calcium hydroxide, chia, papaya, flax, and guava seed extracts. Microbial inoculation was performed using polymicrobial samples from infected root canals, followed by incubation for 7-14 days. Group A samples were sectioned horizontally (3 mm × 3 mm × 2 mm), embedded in acrylic, treated with respective medicaments, and analyzed using confocal microscopy after staining with live/dead bacterial stain. Group B samples were sectioned vertically (4 mm × 2 mm × 2 mm), treated, and subjected to microhardness testing. Seed-based medicaments were prepared by sun-drying, powdering, autoclaving, and mixing with propylene glycol to achieve a homogeneous paste. Results: Chia seed extract showed the highest antimicrobial activity and dentin reinforcement, comparable to calcium hydroxide. Papaya and guava seeds exhibited moderate antibacterial efficacy. Flaxseed demonstrated the lowest performance in both aspects. Calcium hydroxide was effective but did not surpass some natural extracts in mechanical enhancement. Conclusion: Chia and papaya seed extracts present promising alternatives to calcium hydroxide, offering dual functionality - antibacterial efficacy and mechanical reinforcement. These findings support the integration of natural agents in endodontic treatment. Further in vivo and formulation studies are recommended to validate their clinical use.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.