ArticleResearch and practice in thrombosis and haemostasis2026
Epidemiology, therapy, and outcome of immune-mediated thrombotic thrombocytopenic purpura at population level in Germany.
Article in Research and practice in thrombosis and haemostasis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- In reply: epidemiology of immune-mediated thrombotic thrombocytopenic purpura in Germany.Research and practice in thrombosis and haemostasis · 2026Article
- Epidemiology of immune-mediated thrombotic thrombocytopenic purpura in Germany.Research and practice in thrombosis and haemostasis · 2026Article
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Authors and funding
10 authors.
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Abstract
Background: Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a rare, life-threatening thrombotic microangiopathy caused by severe Objectives: We assessed temporal trends in incidence, treatment strategies, and acute in-hospital outcomes of iTTP episodes at the population level in Germany from 2011 to 2021. Methods: This retrospective population-based cohort study used nationwide inpatient data from the German Federal Statistical Office. iTTP cases were identified by International Classification of Disease, Tenth Revision, coding combined with documentation of plasma exchange procedures. Trends were analyzed using linear regression. Results: A total of 2771 iTTP episodes were identified. Incidence of iTTP episodes increased from 2.36 to 3.48 per million inhabitants ( Conclusion: The incidence and severity of iTTP episodes have increased in Germany over the past decade, and treatment strategies have evolved. These findings warrant further research to optimize acute management and understand long-term outcomes.
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