ReviewJournal of Indian Society of Periodontology
Mapping the landscape of antimicrobial peptides in periodontology: A scoping review.
Review in Journal of Indian Society of Periodontology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Antimicrobial peptides (AMPs) are gaining attention as adjunctive agents in periodontal therapy due to their antimicrobial, anti-inflammatory, and host-modulatory properties. Their potential adjunctive applications include use as local drug delivery agents, topical pastes, gels or mouthrinses, reinforcements of membranes or implant surfaces, and other applications. While numerous Objective: This scoping review aimed to map the existing available evidence on AMPs in periodontal therapy, focusing on AMP types, delivery systems, and reported biological, microbiological, and clinical outcomes. Materials and Methods: A systematic literature search was conducted across Medline-PubMed, Cochrane, and Google Scholar for studies published in the past 20 years. Studies were included if they evaluated AMPs for periodontal therapy Results: A total of 21 studies were included, comprising 13 Conclusion: The existing literature proves AMPs to be a promising therapeutic adjunct in periodontal applications. Clinical data, however, are lacking. Bridging the gap between experimental findings and clinical application requires robust translational research, including well-designed human trials, to evaluate safety, efficacy, and long-term outcomes. This scoping review serves as a foundational reference for guiding future studies toward the clinical integration of AMPs in periodontal therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.