ArticleJournal of Indian Society of Periodontology
Assessment of antibiotic resistance in
Article in Journal of Indian Society of Periodontology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Background: Antibiotic resistance poses a major challenge in the control of bacterial infections, including chronic periodontitis. This study aimed to evaluate the antibiotic resistance of Materials and Methods: This study included 24 patients diagnosed with chronic periodontitis, divided into two groups: Group 1 comprised 12 patients with a history of antibiotic exposure within the preceding 6 months and Group 2 comprised 12 patients without any prior antibiotic exposure. GCF samples were collected using sterile absorbent paper points and cultured under anaerobic conditions for the isolation of Results: Patients without prior antibiotic exposure demonstrated a slightly higher mean ZOI (17.66 mm) compared to patients with prior antibiotic exposure (16.66 mm), suggesting marginally better antibiotic effectiveness in the former group. However, this difference was not statistically significant ( Conclusion: The findings indicate a reduced antibiotic effectiveness in patients with previous antibiotic exposure. These results underscore the importance of avoiding empirical antibiotic use and support the consideration of narrow-spectrum antibiotics or alternative treatment approaches, such as local drug delivery systems, to mitigate the development of antibiotic resistance.
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