Evidence map›Paper›PMID 41940190›Full record

ArticleJournal of Indian Society of Periodontology

Development and characterization of a hydrogel containing active principles of lotus leaves (

Akshatha Raj, Rohit Prasad, Bhavya Shetty, Dafney Melissa Rodrigues, Debasmita Das, K Deekshitha, S Gaanashree

Abstract read
In one paragraph

Article in Journal of Indian Society of Periodontology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Akshatha RajDepartment of Periodontology, Faculty of Dental Sciences, Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India.
Rohit PrasadDepartment of Periodontology, Faculty of Dental Sciences, Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India.
Bhavya ShettyDepartment of Periodontology, Faculty of Dental Sciences, Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India.
Dafney Melissa RodriguesDepartment of Periodontology, Faculty of Dental Sciences, Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India.
Debasmita DasDepartment of Periodontology, Faculty of Dental Sciences, Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India.
K DeekshithaDepartment of Periodontology, Faculty of Dental Sciences, Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India.
S GaanashreeDepartment of Periodontology, Faculty of Dental Sciences, Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to formulate and evaluate the antibacterial efficacy of a hydrogel incorporating lotus leaf extract as a potential local drug delivery system for periodontal disease treatment. Materials and Methods: Lotus leaves were extracted using a hydroalcoholic Soxhlet method, and the resulting extract was incorporated into a hydrogel. The antibacterial activity of the hydrogel was assessed Results: The lotus leaf extract demonstrated significant antibacterial activity with an MIC and MBC of 600 μg/mL (0.6 mg/mL) against Conclusion: The lotus leaf extract-based hydrogel showed promising antimicrobial properties and favorable physical characteristics, suggesting its potential as an effective local treatment for periodontitis. These findings highlight the viability of using natural plant extracts in innovative hydrogel formulations to address periodontal disease. Further research is needed to evaluate the lotus leaf extract gel's efficacy, stability, and safety both

Indexed as

Herbal extractlocal drug deliverylotus leavesperiodontitis

Identifiers

PMID41940190
PMCPMC13046345

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.