Evidence map›Paper›PMID 41940072›Full record

ArticleMolecular therapy. Nucleic acids2026

vPE: Toward a new generation of error-free prime editing.

Mahnoor Jamil, Ambreen Zahra, Rizwana Maqbool, Muhammad Imran Arshad, Sultan Habibullah Khan

Abstract readNews
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular therapy. Nucleic acids, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mahnoor JamilCenter for Advanced Studies in Agriculture and Food Security, University of Agriculture, Faisalabad, Pakistan.
Ambreen ZahraCenter for Advanced Studies in Agriculture and Food Security, University of Agriculture, Faisalabad, Pakistan.
Rizwana MaqboolCenter for Advanced Studies in Agriculture and Food Security, University of Agriculture, Faisalabad, Pakistan.
Muhammad Imran ArshadDepartment of Veterinary Preventive Medicine, College of Veterinary Medicine, Qassim University, Buraydah 52571, Kingdom of Saudi Arabia.
Sultan Habibullah KhanCenter for Advanced Studies in Agriculture and Food Security, University of Agriculture, Faisalabad, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prime editing is a precise "search and replace" genome editing tool that enables programmed genome modifications without the need for double-stranded breaks or additional repair templates. However, the retention of the unedited 5' strand hinders the incorporation of stable edits into the genome, and the rate of indel errors is also high. Recently,

Identifiers

PMID41940072
PMCPMC13049633

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.