Evidence map›Paper›PMID 41940063›Full record

ArticleNorthern clinics of Istanbul2026

The impact of mode of delivery on intestinal wall microvascularity in healthy newborns is studied using Superb Microvascular Imaging Doppler technique.

Gul Arga, Gulten Alioglu, Derya Buyukkayhan, Ali Yikilmaz

Abstract read
In one paragraph

Article in Northern clinics of Istanbul, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gul ArgaDepartment of Pediatrics, Istanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkiye.
Gulten AliogluDepartment of Radiology, Istanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkiye.
Derya BuyukkayhanDepartment of Pediatrics, Istanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkiye.
Ali YikilmazDepartment of Radiology, Istanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to investigate whether the mode of delivery influences intestinal microperfusion in healthy term neonates and to evaluate the utility of Superb Microvascular Imaging (SMI) in assessing neonatal intestinal microcirculation.

methodsA total of 45 healthy term neonates born between 38 and 40 weeks of gestation were prospectively enrolled. Twenty-six infants were delivered by cesarean section (C/S) and 19 by normal spontaneous vaginal delivery (NSVD). Intestinal microperfusion was assessed within the first 48 hours of life using monochrome SMI (mSMI) and color SMI (cSMI). Conventional Doppler techniques, including Color Doppler Imaging (CDI), Power Doppler Imaging (PDI), and Advanced Dynamic Flow (ADF), were also performed. Intestinal vascularity was semi-quantitatively scored and compared between groups.

resultsNo significant difference in intestinal microperfusion was observed between neonates delivered by C/S and NSVD using either mSMI (p=0.507) or cSMI (p=0.720). Similarly, no significant differences were detected using CDI, PDI, or ADF. However, mSMI demonstrated significantly higher detection of intestinal vascularity compared to cSMI (p<0.0001) and conventional Doppler modalities, which failed to detect vascular signals in a substantial proportion of cases.

conclusionMode of delivery does not appear to significantly affect early intestinal microperfusion in healthy term neonates. Superb Microvascular Imaging, particularly mSMI, provides a sensitive and non-invasive method for visualizing neonatal intestinal microcirculation. These findings support the potential role of SMI in establishing reference perfusion patterns and in the early detection of gastrointestinal perfusion abnormalities in neonates.

Indexed as

Cesarean sectiondelivery modemicroperfusionnormal spontaneous vaginal deliverySuperb Microvascular Imaging

Identifiers

PMID41940063
PMCPMC13047260

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.