Evidence map›Paper›PMID 41939763›Full record

ArticleFrontiers in medicine2026

Correlation analysis of the extent of lymph node dissection in laparoscopic radical resection of colon cancer and long-term prognosis.

Zhibo Jiao, Shaochuan Yang, Wenyan Chen, Qinhui Ran, Yongjuan Yu

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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Zhibo Jiao *Department of General Surgery, Zhangjiakou First Hospital, Zhangjiakou, Hebei, China.
Shaochuan Yang *Department of General Surgery, Zhangjiakou First Hospital, Zhangjiakou, Hebei, China.
Wenyan ChenDepartment of Endoscopy, Zhangjiakou Fifth Hospital, Zhangjiakou, Hebei, China.
Qinhui RanDepartment of Electrophysiology, Zhangjiakou First Hospital, Zhangjiakou, Hebei, China.
Yongjuan YuDepartment of General Surgery, Zhangjiakou First Hospital, Zhangjiakou, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The extent of lymph node dissection (D1, D2, D3) during laparoscopic radical resection for colon cancer has significant implications on survival, recurrence, and postoperative outcomes. This study aims to compare the effectiveness and safety of these dissection strategies. Methods: A retrospective, multicenter cohort study was conducted, analyzing medical records of 100 patients diagnosed with stage I, II, or III colon cancer. Patients were grouped based on the lymphadenectomy strategy: D1 (reduced), D2 (standard), or D3 (extended). The primary endpoints included overall survival (OS), recurrence rates and disease-free survival (DFS). Secondary endpoints included postoperative complications, and quality of life (QoL). Results: The 5-year survival rate was highest in the D3 group (82%), followed by D2 (75%), and D1 (65%) ( Conclusion: D3 lymphadenectomy provided the best oncological outcomes but increased surgical morbidity, making it suitable for high-risk patients. D2 offered a balanced approach with moderate survival benefits and fewer complications, while D1 may have sufficed for low-risk cases. The choice of dissection strategy should have been individualized based on patient risk factors and tumor characteristics.

Indexed as

colon cancerD1 dissectionD2 dissectionD3 dissectionlymphadenectomysurvival outcomes

Identifiers

PMID41939763
PMCPMC13044137

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.