ArticleFrontiers in medicine2026
Effectiveness of health ecology model-based pulmonary rehabilitation for acute exacerbation of chronic obstructive pulmonary disease: a preliminary study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Background: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) significantly impairs patients' quality of life and survival. While pulmonary rehabilitation (PR) is well-established for stable COPD, evidence for its effectiveness during and after hospitalization for AECOPD remains limited. This study aimed to evaluate the effectiveness of a health ecology model (HEM)-based multidimensional PR intervention compared to conventional care in patients with AECOPD. Methods: This prospective randomized controlled trial enrolled 46 AECOPD patients who, after individual matching, were randomly allocated to either an experimental group or a control group. The experimental group received conventional care supplemented by an HEM-based intervention comprising physiological (assisted sputum removal, progressive breathing exercises, physical training, home-based PR guidance), psychological (peer and caregiver support), and environmental (temperature and humidity regulation) components. The control group received conventional care only, including health education, oxygen therapy, and breathing training during hospitalization. The intervention period spanned from the second day after admission to discharge, with FEV1% reassessed at 8 weeks post-discharge. Outcomes included predicted forced expiratory volume in one second (FEV1%), 6-min walk test (6MWT), modified Medical Research Council dyspnea scale (mMRC), and COPD Assessment Test (CAT). Between-group and within-group differences were analyzed using Student's t-test, with statistical significance set at Results: The experimental group demonstrated significantly greater improvements than the control group in mMRC scores (mean reduction 1.48 vs. 0.87 points, Conclusion: The HEM-based multidimensional PR intervention produced clinically meaningful and statistically significant improvements in lung function and dyspnea in patients hospitalized with AECOPD. These findings support integrating multi-level interventions-including physiological, psychological, and environmental components-into standard care to optimize outcomes in domains that show limited response to conventional rehabilitation alone.
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