Evidence map›Paper›PMID 41939744›Full record

ArticleFrontiers in medicine2026

Combining visual acuity with refraction reduces overestimation of myopia prevalence in school screenings: an age-stratified analysis.

Ningfeng Li, Yu Jiang, Xu Zhang, Wenzhi Huang, Junyan Zhang, Bozheng Zhang, Zongyin Gao, Yunxia Leng

Abstract read
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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Ningfeng LiDepartment of Ophthalmology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Yu JiangDepartment of Ophthalmology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Xu ZhangDepartment of Ophthalmology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Wenzhi HuangDepartment of Ophthalmology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Junyan ZhangClinical Epidemiology and Evidence-Based Medicine, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Taiyuan, China.
Bozheng ZhangCollege of Arts and Sciences, Emory University, Atlanta, GA, United States.
Zongyin GaoDepartment of Ophthalmology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Yunxia LengDepartment of Ophthalmology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: School myopia screening commonly employs non-cycloplegic spherical equivalent refraction (SER ≤ -0. 50 D) for its practicality. However, this SER-only approach likely overestimates the prevalence of visually significant myopia, as it cannot distinguish true myopia from accommodative pseudomyopia, especially in younger children. We quantified the disparity between this SER-only criterion and a combined criterion integrating uncorrected visual acuity (UCVA), the SER + UCVA criterion, and examined its variation across age groups. Methods: This serial cross-sectional study (2018-2021) included 20,750 students aged 5-18 years from Southern China. Myopia was defined using two criteria based on non-cycloplegic measurements in at least one eye: (1) SER-only: SER ≤ -0.50 D; and (2) SER + UCVA: SER ≤ -0.50 D plus age-impaired UCVA (>0.20 logMAR at age 5; >0.00 logMAR at ages ≥6) in the same eye. Age-stratified prevalence estimates were compared. Results: The SER + UCVA criterion yielded consistently lower prevalence estimates than the SER-only criterion (e.g., 48.89% vs. 59.48% in 2021), corresponding to a 15-21% annual relative overestimation. Crucially, this overestimation demonstrated a strong age gradient. It was most severe in young children, with the SER-only myopia prevalence nearly double the SER + UCVA myopia prevalence at ages 5-6 years (relative difference >50%), and progressively narrowed to approximately 10-15% in adolescents (14-18 years). Notably, a significant acceleration in SER + UCVA myopia prevalence was observed in children aged 7-10 years between 2019 and 2020. Furthermore, from age 10 onwards, SER + UCVA myopia prevalence was significantly higher in females than males (all Conclusion: Sole reliance on non-cycloplegic SER substantially overestimates the burden of visually significant myopia, especially in younger children. Incorporating UCVA provides a more accurate and functionally relevant metric for public health screening. We advocate for adopting age-specific SER + UCVA criteria in school-based screenings to optimize referral efficiency, with the greatest benefit expected for younger populations where specificity gains are maximal.

Indexed as

children and adolescentsmyopianon-cycloplegic refractionprevalenceSER + UCVA criterionspherical equivalent refractionvisual acuity

Identifiers

PMID41939744
PMCPMC13043352

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