Evidence map›Paper›PMID 41939719›Full record

ArticleFrontiers in microbiology2026

Methanogenesis from tetramethylammonium and choline in

Jyoti Kashyap, Debdeep Das, Tomislav Ticak, Adam J Creighbaum, Rakhsha Khatri, Donald J Ferguson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jyoti Kashyap *Department of Microbiology, Miami University, Oxford, OH, United States.
Debdeep Das *Department of Microbiology, Miami University, Oxford, OH, United States.
Tomislav TicakDepartment of Microbiology, Miami University, Oxford, OH, United States.
Adam J CreighbaumDepartment of Microbiology, Miami University, Oxford, OH, United States.
Rakhsha KhatriDepartment of Biological Sciences, Miami University Regionals, Hamilton, OH, United States.
Donald J FergusonDepartment of Microbiology, Miami University, Oxford, OH, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methanogenesis is a key biological process contributing to both global climate change and renewable energy via methane. Methylotrophic methanogenesis is an important, but often underappreciated, component of this process. Recently, there has been an increasing interest in methylotrophic methanogenesis from quaternary amines such as glycine betaine, choline, and tetramethylammonium (QMA). QMA was the original quaternary amine identified as a direct substrate for methanogens and the components of its catabolic pathway were isolated from

Indexed as

cholinemethylotrophic methanogenesismethyltransferasepyrrolysinetetramethylammonium

Identifiers

PMID41939719
PMCPMC13044021

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.