Evidence map›Paper›PMID 41939584›Full record

ArticleCureus2026

Spontaneous Intracranial Hemorrhage in Liver Failure: A Case-Based Approach to Transplant Candidacy and Care.

Ramona Nicolau Raducu, Eslam Fouda, Nicolas Caram, Elharith Al-Akeel, Vinaya Manmohansingh, Yehuda Raveh, Gisele J Wakim, Carolina Benjamin, Fouad Souki

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ramona Nicolau RaducuAnesthesiology, Jackson Memorial Hospital, Miami, USA.
Eslam FoudaAnesthesiology, Jackson Memorial Hospital, Miami, USA.
Nicolas CaramAnesthesiology, Jackson Memorial Hospital, Miami, USA.
Elharith Al-AkeelRadiology, Jackson Memorial Hospital, Miami, USA.
Vinaya ManmohansinghAnesthesiology, University of Miami/Jackson Memorial Hospital, Miami, USA.
Yehuda RavehAnesthesiology, University of Miami/Jackson Memorial Hospital, Miami, USA.
Gisele J WakimAnesthesiology, Jackson Memorial Hospital, Miami, USA.
Carolina BenjaminNeurosurgery, Jackson Memorial Hospital, Miami, USA.
Fouad SoukiAnesthesiology, Jackson Memorial Hospital, Miami, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracranial hemorrhage in patients with acute or chronic liver disease is a life-threatening complication with repercussions on both liver transplantation candidacy and perioperative transplant management. This case series and review of the literature details the perioperative management and outcomes of three patients who experienced spontaneous intracranial hemorrhage and subsequently underwent liver transplantation. These cases highlight the challenges encountered in such complex scenarios, emphasizing the critical need for individualized assessments, tailored management strategies, and a multidisciplinary approach to maximize patient outcomes. Moreover, these cases underscore how evolving neurocritical care practice, advances in hemostatic therapies, and improved coordination between transplant and neurology teams can expand access to transplantation. Collectively, these observations contribute to a growing evidence base, supporting nuanced decision-making in situations traditionally considered prohibitive for transplant surgery.

Indexed as

acute liver failurealcohol cirrhosisliver transplantationporto-mesenteric venous thrombosisspontaneous intracranial hemorrhage

Identifiers

PMID41939584
PMCPMC13047340

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.