Evidence map›Paper›PMID 41939560›Full record

ArticleCureus2026

Linezolid-Associated Non-convulsive Status Epilepticus: A Case Report.

Jonathon Chon Teng Chio, Nimmi Wickramasuriya, Tse Chiang Chen, Jaishree Narayanan, Kareem Elzamly

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jonathon Chon Teng ChioDepartment of Pediatric Neurology, University of Oklahoma Health Sciences Center, Oklahoma City, USA.
Nimmi WickramasuriyaDepartment of Neurology, Tulane University School of Medicine, New Orleans, USA.
Tse Chiang ChenDepartment of Neurology, Northwestern University Feinberg School of Medicine, Chicago, USA.
Jaishree NarayananDepartment of Neurology, Tulane University School of Medicine, New Orleans, USA.
Kareem ElzamlyDepartment of Neurology, University of Texas at Houston, Houston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neural, metabolic, and myelosuppressive side effects can occur upon administration of linezolid (LNZ), which is an antibiotic that can cause seizures through multiple mechanisms. Here, we describe the case of a 77-year-old woman who initially presented with a subdural hematoma (SDH). She subsequently developed non-convulsive status epilepticus (NCSE), a category of seizure that can occur secondary to antibiotic use. These episodes persisted despite being treated by multiple anti-epileptic medications, but resolved upon cessation of linezolid. This case is important because it highlights how the appropriate use of a drug can still cause a serious neurological side effect that can negatively impact patient outcomes.

Indexed as

antibioticantibiotic-induced seizureslinezolidnon-convulsive status epilepticusseizures

Identifiers

PMID41939560
PMCPMC13050277

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.