Evidence map›Paper›PMID 41939544›Full record

ArticleCureus2026

Successful Treatment With Rituximab for Severe Immune Thrombocytopenic Purpura During Hemodialysis.

Mayuko Hanyuda, Yukihiro Wada, Tomomi Motohashi, Kiho Yanagisawa, Genichi Saito, Ryota Uchitsubo, Sayumi Kawamura, Shun Sakurabayashi, Kazuhiro Takeuchi, Shokichi Naito and 1 more

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mayuko HanyudaDepartment of Nephrology, Kitasato University School of Medicine, Sagamihara, JPN.
Yukihiro WadaDepartment of Nephrology, Kitasato University School of Medicine, Sagamihara, JPN.
Tomomi MotohashiDepartment of Nephrology, Kitasato University School of Medicine, Sagamihara, JPN.
Kiho YanagisawaDepartment of Nephrology, Kitasato University School of Medicine, Sagamihara, JPN.
Genichi SaitoDepartment of Nephrology, Kitasato University School of Medicine, Sagamihara, JPN.
Ryota UchitsuboDepartment of Nephrology, Kitasato University School of Medicine, Sagamihara, JPN.
Sayumi KawamuraDepartment of Nephrology, Kitasato University School of Medicine, Sagamihara, JPN.
Shun SakurabayashiDepartment of Nephrology, Kitasato University School of Medicine, Sagamihara, JPN.
Kazuhiro TakeuchiDepartment of Nephrology, Kitasato University School of Medicine, Sagamihara, JPN.
Shokichi NaitoDepartment of Nephrology, Kitasato University School of Medicine, Sagamihara, JPN.
Yasuo TakeuchiDepartment of Nephrology, Kitasato University School of Medicine, Sagamihara, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune thrombocytopenic purpura (ITP), an autoimmune disorder characterized by peripheral platelet destruction, is uncommon in patients undergoing hemodialysis, who have an inherently elevated bleeding risk. We report a case of severe ITP in a 68-year-old woman on maintenance hemodialysis for 10 years due to myeloperoxidase-anti-neutrophil cytoplasmic antibody (MPO-ANCA)-associated glomerulonephritis, treated with rituximab. Three years before admission, she was diagnosed with rheumatoid arthritis (RA) and had unexplained thrombocytopenia that improved with prednisolone, resolving her arthritis. The disease activity of both MPO-ANCA-associated vasculitis and RA was later controlled without prednisolone. Four months prior, her platelet count suddenly dropped to 54,000/μL. Laboratory tests showed elevated platelet-associated IgG (PA-IgG), increased bone marrow megakaryocytes, negative antinuclear antibody, MPO-ANCA, anti-

Indexed as

bleeding riskhemodialysisimmune thrombocytopenic purpuramyeloperoxidase-anti-neutrophil cytoplasmic antibody (mpo-anca)rituximab

Identifiers

PMID41939544
PMCPMC13044668

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.