Evidence map›Paper›PMID 41939267›Full record

ArticleFrontiers in psychiatry2025

Implementation and evaluation of family-based interventions within the Germany-wide Children of Mentally Ill Parents-network: study protocol for three prospective, rater-blinded, cluster-randomized controlled multicenter trials.

Theresa Paumen, Anna Leidger, Joana Ralfs, Anna Modarressi, Ann-Kathrin Ozga, Annika Möhl, Anne Daubmann, Antonia Zapf, Tamara Waldmann, Carolin von Gottberg and 71 more

Registry-linked trialAbstract read
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In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04369625 (Cross-sector Care for Children and Adolescents With Mentally Ill and Addicted Parents - Children of Mentally Ill Parents -Network - CHIMPS-NET), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04369625 nacompletednot on this map

Cross-sector Care for Children and Adolescents With Mentally Ill and Addicted Parents - Children of Mentally Ill Parents -Network - CHIMPS-NET

TypeinterventionalSponsorSilke Wiegand-Grefe, Prof. Dr.Ran2020 to 2023Enrolled406ConditionsMental Health IssueArmsCHIMPS-T, CHIMPS-P, CHIMPS-MFT-group, iCHIMPS
3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

81 authors.

Theresa PaumenDepartment of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Anna LeidgerDepartment of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Joana RalfsDepartment of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Anna ModarressiDepartment of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ann-Kathrin OzgaInstitute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Annika MöhlInstitute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Anne DaubmannInstitute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Antonia ZapfInstitute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Tamara WaldmannUniversity of Ulm, Department of Psychiatry II, Section: Health Economics and Health Services Research, Bezirkskrankenhaus Günzburg, Günzburg, Germany.
Carolin von GottbergUniversity of Ulm, Department of Psychiatry II, Section: Health Economics and Health Services Research, Bezirkskrankenhaus Günzburg, Günzburg, Germany.
Reinhold KilianUniversity of Ulm, Department of Psychiatry II, Section: Health Economics and Health Services Research, Bezirkskrankenhaus Günzburg, Günzburg, Germany.
Nicolas PardeyCenter for Health Economics Research Hannover (CHERH), Leibniz University Hannover, Hanover, Germany.
Jan ZeidlerCenter for Health Economics Research Hannover (CHERH), Leibniz University Hannover, Hanover, Germany.
Timo BeekerCenter for Mental Health, Immanuel Klinik Rüdersdorf, University Hospital of Brandenburg Medical School Theodor Fontane, Rüdersdorf, Germany.
Sebastian von PeterCenter for Mental Health, Immanuel Klinik Rüdersdorf, University Hospital of Brandenburg Medical School Theodor Fontane, Rüdersdorf, Germany.
Martin HeinzeCenter for Mental Health, Immanuel Klinik Rüdersdorf, University Hospital of Brandenburg Medical School Theodor Fontane, Rüdersdorf, Germany.
Silke PawilsDepartment of Medical Psychology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Anna K GeorgInstitute for Psychosocial Prevention, Centre for Psychosocial Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Svenja TaubnerInstitute for Psychosocial Prevention, Centre for Psychosocial Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Olga PiwkowskaCharité - Universitätsmedizin Berlin, Department of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, Berlin, Germany.
Sibylle M WinterGerman Center for Mental Health (DZPG), Berlin, Germany.
Ruth LingnauDepartment of Evaluation and Implementation Research, aQua Institute for Applied Quality Improvement and Research in Health Care GmbH, Göttingen, Germany.
Carina StammannDepartment of Evaluation and Implementation Research, aQua Institute for Applied Quality Improvement and Research in Health Care GmbH, Göttingen, Germany.
Gerald WillmsDepartment of Evaluation and Implementation Research, aQua Institute for Applied Quality Improvement and Research in Health Care GmbH, Göttingen, Germany.
Farhad RezvaniDepartment of Medical Psychology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Jörg DirmaierDepartment of Medical Psychology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Koralia SeklerAFET Federal Association for Educational Assistance, Registered Association, Hanover, Germany.
Birgit GörresCommunity Psychiatry Umbrella Organization, Registered Association, Cologne, Germany.
Jürgen GallinatDepartment of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Martin LambertDepartment of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Sarah HohmannDepartment of Child and Adolescent Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Martin DriessenEvangelisches Klinikum Bethel gGmbH, Department of Psychiatry and Psychotherapy, University Medical Center Ostwestfalen-Lippe (OWL), Bielefeld University, Bielefeld, Germany.
Michael SiniatchkinUniversity Clinic for Child and Adolescent Psychiatry and Psychotherapy, Protestant Hospital Bethel, University Clinics Ostwestfalen-Lippe, Bielefeld, Germany.
Frank JessenDepartment of Psychiatry, Medical Faculty, University of Cologne, Cologne, Germany.
Stephan BenderFaculty of Medicine and University Hospital Cologne, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Cologne, Cologne, Germany.
Felix BermpohlDepartment of Psychiatry and Psychotherapy, Charité Campus St. Hedwig Hospital, Berlin, Germany.
Andreas HeinzDepartment of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Berlin, Germany.
Christoph U CorrellCharité - Universitätsmedizin Berlin, Department of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, Berlin, Germany.
Christine Rummel-KlugeDepartment of Psychiatry and Psychotherapy, Medical Faculty, Leipzig University, Leipzig, Germany.
Ulrich W SeidlDepartment of Psychiatry and Psychotherapy, Saarland-Heilstätten GmbH (SHG)-Kliniken Saarbrücken, Saarbrücken, Germany.
Eva MöhlerDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Saarland University Medical Center, Homburg, Germany.
Katharina DomschkeGerman Center for Mental Health (DZPG), Berlin, Germany.
Christian FleischhakerDepartment of Child and Adolescent Psychiatry and Psychotherapy, University Medical Center Freiburg, Freiburg, Germany.
Markus JägerDepartment of Psychiatry, Psychotherapy and Psychosomatic, District Hospital Kempten, Kempten, Germany.
Michele NoterdaemeDepartment of Child and Adolescent Psychiatry and Psychotherapy KJF Klinik Josefinum, Augsburg, Germany.
Frank GuderianDepartment of Child and Adolescent Psychiatry and Psychotherapy KJF Klinik Josefinum, Augsburg, Germany.
Tomasz Antoni JarczokDepartment of Child and Adolescent Psychiatry and Psychotherapy KJF Klinik Josefinum, Augsburg, Germany.
Michael KölchDepartment of Child and Adolescent Psychiatry, Neurology, Psychosomatics and Psychotherapy, Rostock University Medical Center, Rostock, Germany.
Roland BurghardtDepartment of Child and Adolescent Psychiatry, Klinikum Frankfurt/Oder, Frankfurt, Germany.
Klaus-Thomas KronmüllerDepartment of General Psychiatry and Psychotherapy, Landschaftsverband Westfalen-Lippe (LWL) Hospital Gütersloh, Gütersloh, Germany.
Fabian KleinDepartment of General Psychiatry and Psychotherapy, Landschaftsverband Westfalen-Lippe (LWL) Hospital Gütersloh, Gütersloh, Germany.
Martin HoltmannLWL-University Hospital for Child and Adolescent Psychiatry, Ruhr-University Bochum, Hamm, Germany.
Andreas J FallgatterDepartment of Psychiatry and Psychotherapy, University Hospital of Tübingen, Tübingen, Germany.
Tobias J RennerDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Psychiatry and Psychotherapy, Tübingen, Germany.
Gerd Schulte-KörneDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LMU University Hospital, LMU Munich, Munich, Germany.
Belinda PlattDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LMU University Hospital, LMU Munich, Munich, Germany.
Thomas FrodlDepartment of Psychiatry and Psychotherapy and Center for Behavioral Brain Sciences, Otto von Guericke University of Magdeburg, Magdeburg, Germany.
Hans-Henning FlechtnerClinic for Child and Adolescent Psychiatry and Psychotherapy, University of Magdeburg, Magdeburg, Germany.
Christian HaaseClinic for Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Helios Clinics Schwerin, Schwerin, Germany.
Stephanie MehlDepartment of Psychiatry and Psychotherapy & Center for Mind, Brain and Behavior, University of Marburg (Philipps Universität), Marburg, Germany.
Katja BeckerDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Marburg and University of Marburg (Philipps Universität), Marburg, Germany.
Sylvia ClausDepartment of Psychiatry, Psychosomatics und Psychotherapy, Pfalzklinikum, Klingenmünster, Germany.
Tina In-AlbonClinical Child and Adolescent Psychology and Psychotherapy, University of Kaiserslautern-Landau, Landau, Germany.
Ralf SchlößerClinic for Psychiatry, Psychotherapy and Psychosomatics, Helios Hospital Erfurt, Erfurt, Germany.
Ekkehart EnglertClinic for Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, Helios Hospital Erfurt, Erfurt, Germany.
Thomas BeckerDepartment of Psychiatry II, Ulm University, Ulm, Germany.
Andreas ReifDepartment of Psychiatry, Psychosomatic Medicine and Psychotherapy, Goethe University Frankfurt, Frankfurt am Main, Germany.
Michael BernerPsychiatry and Psychotherapeutic Medicine, Municipal Clinical Center of Karlsruhe, Karlsruhe, Germany.
Simone BornPsychiatry and Psychotherapeutic Medicine, Municipal Clinical Center of Karlsruhe, Karlsruhe, Germany.
Meike BottlenderChild and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Municipal Clinical Center of Karlsruhe, Karlsruhe, Germany.
Ursula MarschallStatutory Health Insurance, BARMER, Wuppertal, Germany.
Luisa SchäferStatutory Health Insurance, Techniker Krankenkasse, Hamburg, Germany.
Sophia RocabadoStatutory Health Insurance, Deutsche Angestellten-Krankenkasse(DAK)-Gesundheit, Hamburg, Germany.
Thomas KrullStatutory Health Insurance, Mobil Krankenkasse, Celle, Germany.
Michél HenkelStatutory Health Insurance, Kaufmännische Krankenkasse Halle (KKH) Kaufmännische Krankenkasse, Hanover, Germany.
Alice BrinkmannStatutory Health Insurance, Kaufmännische Krankenkasse Halle (KKH) Kaufmännische Krankenkasse, Hanover, Germany.
Jana LübkeStatutory Health Insurance, Allgemeine Ortskrankenkasse Baden-Württemberg, Stuttgart, Germany.
Heike PlachetkaStatutory Health Insurance, Allgemeine Ortskrankenkasse (AOK) - Die Gesundheitskasse in Hessen, Bad Homburg, Germany.
Steve HüttmannStatutory Health Insurance, Innungskrankenkasse (IKK) classic, Dresden, Germany.
Florian BrandtStatutory Health Insurance, Innungskrankenkasse (IKK) Südwest, Saarbrücken, Germany.
Silke Wiegand-GrefeDepartment of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Children of mentally ill parents have an increased risk of developing a mental illness. From an ethical and health-economic perspective, psychotherapeutic care for this risk group is necessary to counter the risk of transgenerational transmission of mental illness. The psychosocial situation of affected families is complex and requires customized support. Within the Children-of-Mentally-Ill-Parents-Network (CHIMPS-NET), three family-based, needs-tailored new forms of care (NFC) - based on the manualized CHIMPS intervention - are implemented and evaluated at 21 locations in Germany. The online intervention iCHIMPS is described in a separate study protocol. Methods: For each NFC, a prospective, rater-blinded, cluster-randomized, controlled study is conducted. Data is collected from the perspective of both parents, all children aged 8 years and older, external raters and therapists at four measurement points: at baseline (T1) and 6 (T2), 12 (T3) and 18 (T4) months after randomization. Allocation to the respective trials is based on baseline assessments of children's mental health symptoms/diagnoses and family functionality, which is followed by randomization. We hypothesize that children in the intervention groups (IGs) have fewer parent-reported mental health problems at T3 than in the respective control groups (CGs), which receive Treatment-as-Usual (TAU). The biometric effect evaluation is supplemented by health economic evaluations and a qualitative evaluation. Discussion: CHIMPS-NET has both raised awareness for children of mentally ill parents and enabled various stakeholders to network with each other. The network contributes to evidence-based care for this risk group. An update of the CHIMPS manual regarding the customized NFC is in process. Clinical trial registration: https://www.bfarm.de/DE/Das-BfArM/Aufgaben/Deutsches-Register-Klinischer-Studien/_node.html; DRKS00020380; https://www.clinicaltrials.gov: NCT04369625.

Indexed as

family therapynew forms of carepsychodynamic work with familiespsychosocial preventionpsychotherapy researchtransgenerational mental illness

Identifiers

PMID41939267
PMCPMC13045562

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