Evidence map›Paper›PMID 41939228›Full record

ArticleJournal of surgical case reports2026

Thoracic aortic rupture in a patient with repeated oral fluoroquinolone administration.

Masahiko Narita, Nobuyuki Akasaka, Kentaro Shirakura, Hana Fukuta, Tomoki Nakatsu, Hiroyuki Kamiya

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of surgical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Masahiko NaritaDepartment of Cardiovascular Surgery, Steel Memorial Muroran Hospital, Chiribetsucho 1-45, Muroran 050-0076, Japan.ORCID https://orcid.org/0000-0001-8150-2552
Nobuyuki AkasakaDepartment of Cardiovascular Surgery, Steel Memorial Muroran Hospital, Chiribetsucho 1-45, Muroran 050-0076, Japan.
Kentaro ShirakuraDepartment of Cardiac Surgery, Asahikawa Medical University, Midorigaoka Higashi 2-1-1-1, Asahikawa 078-8510, Japan.
Hana FukutaDepartment of Cardiovascular Surgery, Steel Memorial Muroran Hospital, Chiribetsucho 1-45, Muroran 050-0076, Japan.
Tomoki NakatsuDepartment of Cardiovascular Surgery, Steel Memorial Muroran Hospital, Chiribetsucho 1-45, Muroran 050-0076, Japan.
Hiroyuki KamiyaDepartment of Cardiac Surgery, Asahikawa Medical University, Midorigaoka Higashi 2-1-1-1, Asahikawa 078-8510, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluoroquinolones (FQs) are widely used antibiotics with a broad antibacterial spectrum. However, recent studies have raised concerns regarding the potential association of FQs with an increased risk of aortic aneurysm and aortic dissection. We report a case of an older patient with stable blood pressure and no aortic dilation who developed a thoracic aortic rupture following repeated FQ administration. Although a direct causal relationship between FQ exposure and aortic rupture remains unproven in this single case, this case suggests the need for careful monitoring for possible aortic events, particularly in older patients requiring repeated FQ therapy.

Indexed as

adverse drug reactionaortic aneurysmaortic rupturefluoroquinolonelevofloxacinthoracic endovascular aortic repair

Identifiers

PMID41939228
PMCPMC13045826

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.