Evidence map›Paper›PMID 41939215›Full record

ArticleInternational journal of nanomedicine2026

An Experimental Study into the Photodynamic/Sonodynamic Therapy of Triple-Negative Breast Cancer Mediated by the Novel Nano-Photonic Sensitizer NBDPBr Nanoparticles.

Qian Huang, Leichen Wang, Yaqi Zhang, Lilin Zhao, Ting Zhang

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qian HuangDepartment of Ultrasound, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing, Jiangsu, 210009, People's Republic of China.
Leichen WangKey Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (NanjingTech), Nanjing, Jiangsu, 211800, People's Republic of China.
Yaqi ZhangDepartment of Ultrasound, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing, Jiangsu, 210009, People's Republic of China.
Lilin ZhaoDepartment of Ultrasound, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing, Jiangsu, 210009, People's Republic of China.
Ting ZhangDepartment of Ultrasound, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing, Jiangsu, 210009, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to develop a synergistic photodynamic therapy/sonodynamic therapy (PDT/SDT) system that utilises novel NBDPBr nanoparticles (NPs). These NBDPBr NPs are composed of the aza-boron-dipyrromethene (Aza-BODIPY) dye NBDPBr, which is encapsulated in amphiphilic polymer F-127 (Pluronic Methods: The photophysical properties of the NBDPBr NPs were characterised. Singlet oxygen ( Results: The spherical NBDPBr NPs showed excellent stability, with an average diameter of about 82.9 nm. Combined laser and ultrasound irradiation induced the highest Conclusion: NBDPBr NPs mediate potent synergistic PDT/SDT against TNBC, supported by a dual-modal URM/PAI imaging platform for treatment monitoring. This study presents a promising theranostic strategy with high translational potential for TNBC management.

Indexed as

Boron CompoundsNanoparticlesPhotochemotherapyPhotosensitizing AgentsTriple Negative Breast NeoplasmsUltrasonic TherapyAnimalsCell Line, TumorCell SurvivalFemaleHumansMiceMice, Inbred BALB CReactive Oxygen SpeciesBoron CompoundsPhotosensitizing AgentsReactive Oxygen Speciesmultimodal imagingnanoparticlephotodynamic therapyphotosensitizerssonodynamic therapysynergistic therapytriple-negative breast cancer

Identifiers

PMID41939215
PMCPMC13044455

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.