Evidence map›Paper›PMID 41939137›Full record

ArticleCurrent research in food science2026

Fabrication and antibacterial properties of self-assembled lysozyme nanofilms induced by reduced glutathione.

Can Wu, Qiuyue Hou, Hongyu Liang, Xuefeng Zhang, Bing Cui, Yuying Hu, Xin Shi, Bin Zhou

Abstract read
In one paragraph

Article in Current research in food science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Can WuKey Laboratory of Fermentation Engineering (Ministry of Education), Hubei Key Laboratory of Industrial Microbiology, School of Life and Health Sciences, Hubei University of Technology, Wuhan, China.
Qiuyue HouKey Laboratory of Fermentation Engineering (Ministry of Education), Hubei Key Laboratory of Industrial Microbiology, School of Life and Health Sciences, Hubei University of Technology, Wuhan, China.
Hongyu LiangKey Laboratory of Fermentation Engineering (Ministry of Education), Hubei Key Laboratory of Industrial Microbiology, School of Life and Health Sciences, Hubei University of Technology, Wuhan, China.
Xuefeng ZhangTechnology Center, China Tobacco Fujian Industrial Co., Ltd., Xiamen, China.
Bing CuiKey Laboratory of Fermentation Engineering (Ministry of Education), Hubei Key Laboratory of Industrial Microbiology, School of Life and Health Sciences, Hubei University of Technology, Wuhan, China.
Yuying HuKey Laboratory of Fermentation Engineering (Ministry of Education), Hubei Key Laboratory of Industrial Microbiology, School of Life and Health Sciences, Hubei University of Technology, Wuhan, China.
Xin ShiKey Laboratory of Fermentation Engineering (Ministry of Education), Hubei Key Laboratory of Industrial Microbiology, School of Life and Health Sciences, Hubei University of Technology, Wuhan, China.
Bin ZhouKey Laboratory of Fermentation Engineering (Ministry of Education), Hubei Key Laboratory of Industrial Microbiology, School of Life and Health Sciences, Hubei University of Technology, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study developed a self-assembled lysozyme nanofilm at the air-water interface using reduced glutathione (GSH) as an inducer, demonstrating broad-spectrum antibacterial activity and tunable functionality. Through thiol-disulfide exchange, GSH reduces the disulfide bonds in lysozyme, leading to protein unfolding and conformational transition from α-helix to β-sheet-rich structures. The assembly process, along with film morphology and surface properties, can be effectively modulated by varying lysozyme concentration and environmental pH, enabling the rational design of surface charge and hydrophobicity to optimize antibacterial performance. The resulting nanofilm demonstrates significant antibacterial efficacy against both

Indexed as

Antibacterial activityLysozymeNanofilmReduced glutathioneSelf-assembly

Identifiers

PMID41939137
PMCPMC13050106

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.