ArticleAnnals of medicine and surgery (2012)2026
Intravenous vitamin C for bleeding control in elective C-sections: a randomized clinical trial study.
Article in Annals of medicine and surgery (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
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Abstract
Objective: This study aimed to evaluate whether intravenous vitamin C reduces intraoperative and postoperative blood loss in elective cesarean deliveries, with primary outcomes focusing on hemoglobin preservation and quantified blood loss measurements. Methods: In this randomized trial, 60 women undergoing elective morning cesarean sections (CS) were assigned to receive either 1 g Intravenous (IV) vitamin C (n = 30) or placebo (n = 30) 2 hours preoperatively. The primary endpoint was the change in hemoglobin level from preoperative baseline to 24 hours postoperative. Secondary outcomes included quantified blood loss (suction volume, weighed gauze/sponges), uterotonic requirements, and procedure duration. Results: Baseline characteristics showed no significant differences between groups. The vitamin C intervention group demonstrated superior outcomes across multiple measures: intraoperative gauze use was reduced by 30% (4.43 ± 1.04 vs 6.37 ± 1.29, Conclusion: Prophylactic vitamin C significantly reduces intraoperative blood loss and preserves hemoglobin during elective CS, while shortening procedure time and decreasing uterotonic needs. These clinically meaningful benefits support its use as a safe adjuvant therapy.
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