ArticleAmerican heart journal plus : cardiology research and practice2026
Heart rate circadian rhythm in patients with traumatic brain injury: A retrospective analysis of a nationwide multicenter ICU database.
Article in American heart journal plus : cardiology research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Objective: This study aimed to determine whether the circadian rhythm in heart rate independently associated with in-hospital mortality among patients with TBI. Methods: Data were extracted from the eICU-CRD. Heart rate circadian rhythm was characterized using three parameters: mesor, amplitude, and peak time. The prognostic association and incremental discriminatory value of these circadian variables, alongside the APACHE IV score, was assessed in relation to in-hospital mortality. Results: Among 3202 patients showing a circadian rhythm in heart rate, each 10-beat/min increase in mesor was associated with a 1.18-fold higher odd of in-hospital mortality (95% CI: 1.08-1.30; Conclusion: Circadian rhythm features of heart rate are independent prognostic factors associated with in-hospital mortality in TBI patients. Integrating these variables with conventional scoring systems may improve prognostic accuracy.
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