Evidence map›Paper›PMID 41938889›Full record

Trial reportClinics in orthopedic surgery2026

The Minimal Clinically Important Difference of the American Orthopaedic Foot and Ankle Society Ankle Hindfoot Scale in Patients with Unstable Ankle Fracture.

Jasper Tausendfreund, Diederick Penning, Ewan Ritchie, Bas Twigt, Pieter Joosse, Susan van Dieren, Tim Schepers

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Clinics in orthopedic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jasper TausendfreundTrauma Unit, Amsterdam University Medical Center, Amsterdam Movement Sciences, Amsterdam, the Netherlands.ORCID https://orcid.org/0009-0006-8479-9076
Diederick PenningTrauma Unit, Amsterdam University Medical Center, Amsterdam Movement Sciences, Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0003-1355-1322
Ewan RitchieTrauma Unit, Alrijne Hospital Group, Leiden, the Netherlands.ORCID https://orcid.org/0000-0001-5988-2165
Bas TwigtTrauma Unit, BovenIJ Hospital, Amsterdam, the Netherlands.ORCID https://orcid.org/0009-0003-8397-538X
Pieter JoosseTrauma Unit, Noordwest Hospital Group, Alkmaar, the Netherlands.ORCID https://orcid.org/0000-0003-1712-677X
Susan van DierenTrauma Unit, Amsterdam University Medical Center, Amsterdam Movement Sciences, Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0002-3084-0495
Tim SchepersTrauma Unit, Amsterdam University Medical Center, Amsterdam Movement Sciences, Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0003-1172-4939

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Backgroud: The American Orthopaedic Foot and Ankle Society (AOFAS) Ankle Hindfoot Scale is frequently used as a patient-reported outcome measure (PROM) to evaluate recovery trajectories following foot and ankle injuries. This study aimed to determine the minimal clinically important difference (MCID) for the AOFAS score in patients with surgically treated unstable ankle fractures. Methods: Data were obtained from the ROutine versus on DEmand removal Of the syndesmotic stabilisation screw (RODEO) trial, a multicenter randomized controlled trial evaluating the management of syndesmotic screw fixation following ankle fracture surgery. Eligible patients completed the AOFAS scale at 3, 6, and 12 months postoperatively. The MCID was calculated using both anchor-based approaches (mean change, receiver operating characteristic [ROC] analysis) and distribution-based approaches (minimal detectable change [MDC] and 0.5 standard deviation). Results: A total of 148 patients were included, with a mean age of 47 years, and a male predominance of 63.5%. Median AOFAS scores improved significantly over time, rising from 73.0 at 3 months to 85.0 at 12 months postoperatively ( Conclusions: Despite the extended recovery period, often up to 12 months, following surgical stabilization of unstable ankle fractures with syndesmotic injury, the AOFAS remains one of the most utilized PROMs in this context. Based on these findings, a change in score between 4.1 and 7.8 points should be considered clinically relevant at the 1-year follow-up.

Indexed as

Ankle FracturesFracture Fixation, InternalMinimal Clinically Important DifferenceAdultFemaleHumansMaleMiddle AgedPatient Reported Outcome MeasuresAmerican Orthopaedic Foot and Ankle SocietyAnkle fractureMinimal clinically important differencePatient reported outcome measures

Identifiers

PMID41938889
PMCPMC13047390

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.