Evidence map›Paper›PMID 41938863›Full record

ArticleFrontiers in cellular and infection microbiology2026

TM9SF4 acts as a receptor mediating

Li Lei, Shiyu Xu, Zhen Yang, Xingyu Pan, Jiali Xu, Senyan Du, Qin Zhao, Xiaobo Huang, Sanjie Cao, Rui Wu and 3 more

Abstract read
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In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Li Lei *Research Center for Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Shiyu Xu *Institute of Urban Agriculture, Chinese Academy of Agricultural Sciences, Chengdu Agricultural Science and Technology Center, Chengdu, China.
Zhen Yang *Chongqing Academy of Animal Sciences, Chongqing, China.
Xingyu PanResearch Center for Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Jiali XuResearch Center for Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Senyan DuResearch Center for Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Qin ZhaoResearch Center for Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Xiaobo HuangResearch Center for Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Sanjie CaoResearch Center for Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Rui WuResearch Center for Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Yiping WangResearch Center for Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Qigui YanResearch Center for Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Yiping WenResearch Center for Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cytolethal Distending Toxin (CDT) is the only exotoxin that Methods: This study employed Co-immunoprecipitation (Co-IP) combined with Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) to identify potential host proteins interacting with Results: We identified 287 proteins in PK15 cells that potentially interact with Conclusion: We initially proposed TM9SF4 as a receptor for

Indexed as

Bacterial ToxinsEpithelial CellsHaemophilus parasuisHost-Pathogen InteractionsAnimalsApoptosisCell LineChromatography, LiquidGene Knockout TechniquesImmunoprecipitationSwineTandem Mass SpectrometryVirulenceBacterial Toxinscytolethal distending toxincell receptorCytolethal Distending ToxinGlaesserella parasuisinteraction proteinsTM9SF4

Identifiers

PMID41938863
PMCPMC13043650

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.