Evidence map›Paper›PMID 41938821›Full record

ArticleEuropean heart journal open2026

Circulating biomarkers and mortality in atrial fibrillation: the REasons for Geographic And Racial Differences in Stroke study.

Erin M Hald, Katherine Wilkinson, Samuel A P Short, Suzanne E Judd, Virginia J Howard, Emily B Levitan, Elsayed Z Soliman, Mary Cushman

Abstract read
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In one paragraph

Article in European heart journal open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Erin M HaldDepartment of Medicine, Larner College of Medicine at the University of Vermont, 89 Beaumont Ave, Burlington, VT 05405, USA.ORCID https://orcid.org/0009-0005-1459-7500
Katherine WilkinsonDepartment of Medicine, Larner College of Medicine at the University of Vermont, 89 Beaumont Ave, Burlington, VT 05405, USA.ORCID https://orcid.org/0000-0001-6190-735X
Samuel A P ShortDepartment of Medicine, Larner College of Medicine at the University of Vermont, 89 Beaumont Ave, Burlington, VT 05405, USA.ORCID https://orcid.org/0000-0002-3847-4768
Suzanne E JuddDepartment of Biostatistics, University of Alabama at Birmingham, 1665 University Boulevard, Room 327, Birmingham, AL 35294, USA.ORCID https://orcid.org/0000-0001-7594-6587
Virginia J HowardDepartment of Epidemiology, University of Alabama at Birmingham, 1720 2nd Ave S, Birmingham, AL 35294-0022, USA.ORCID https://orcid.org/0000-0003-4912-9975
Emily B LevitanDepartment of Epidemiology, University of Alabama at Birmingham, 1720 2nd Ave S, Birmingham, AL 35294-0022, USA.ORCID https://orcid.org/0000-0002-5429-3852
Elsayed Z SolimanEpidemiological Cardiology Research Center, Department of Internal Medicine, Section on Cardiovascular Medicine, Wake Forest School of Medicine, 525 Vine St, Winston-Salem, NC 27101, USA.ORCID https://orcid.org/0000-0001-5632-8150
Mary CushmanDepartment of Medicine, Larner College of Medicine at the University of Vermont, 89 Beaumont Ave, Burlington, VT 05405, USA.ORCID https://orcid.org/0000-0002-7871-6143

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Examination of biomarkers associated with mortality among people with atrial fibrillation (AF) may help identify possible preventive interventions in this high-risk population. We aimed to study associations of circulating biomarkers with all-cause and cause-specific mortality in persons with AF in the US national biracial REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort. Methods and results: REGARDS enrolled 30 239 Black and White adults aged ≥45 in 2003-07. Candidate biomarkers were measured in all participants with baseline AF and no prior stroke ( Conclusion: Several biomarkers were associated with all-cause and cardiovascular mortality in AF, suggesting multiple domains of clinical relevance that support interventions to reduce mortality.

Indexed as

Atrial fibrillationBiomarkersCohort studyMortality

Identifiers

PMID41938821
PMCPMC13043327

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.