ArticleThe Pan African medical journal2026
Symptom burden and its effect on the quality of life in a selected group of breast cancer patients in Delta State (Nigeria) after chemotherapy: a cross-sectional study.
Article in The Pan African medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: breast cancer remains a significant global health burden, with chemotherapy serving as a cornerstone of treatment. However, chemotherapy is associated with a high symptom burden, adversely impacting patients' quality of life. This study assessed the prevalence, severity, and impact of symptom burden among breast cancer patients undergoing chemotherapy in Delta State, Nigeria. Methods: a cross-sectional design was utilized, and data were analyzed using Chi-square tests to examine associations between symptom burden and sociodemographic factors, cancer stage, and overall well-being. The researchers purposively recruited 139 participants of the 195 patients from the Oncology Clinics of Delta State University Teaching Hospital, Oghara, and Federal Medical Centre, Asaba, both in Delta State, Nigeria. Results: findings revealed that 36% of patients experienced moderate symptom burden, while 35.3% had severe or very severe burden. Pain (80%), fatigue (65%), and sleep disturbances (60%) were the most common symptoms. Marital status (χ Conclusion: this study underscores the importance of individualized supportive care tailored to symptom profiles, particularly for patients with advanced-stage disease and those lacking social support. Addressing symptom burden holistically can improve treatment adherence, resilience, and overall well-being in breast cancer survivors.
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