Evidence map›Paper›PMID 41938672›Full record

ArticleCureus2026

Multiple Opportunistic Infections as the Initial Presentation of Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) in an Ecuadorian Immigrant.

Uma Alappan, Trevan Klug, Jessica Magid-Bernstein, Anita Huttner, Joseph Vinetz

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Uma AlappanInternal Medicine, Yale School of Medicine, New Haven, USA.
Trevan KlugPathology, Yale School of Medicine, New Haven, USA.
Jessica Magid-BernsteinNeurology, Yale School of Medicine, New Haven, USA.
Anita HuttnerPathology, Yale School of Medicine, New Haven, USA.
Joseph VinetzInfectious Disease, Yale School of Medicine, New Haven, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advanced human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) continues to occur in those with social, educational, and cultural barriers to accessing healthcare. A 27-year-old Ecuadorian man presented with vomiting, epigastric pain, fever, weakness, and weight loss. He had advanced AIDS, with opportunistic infections including disseminated histoplasmosis, cerebral toxoplasmosis, and JC virus brain infection. Despite prior repeated contact with local, US-based healthcare, sexual history and HIV screening were never performed. Missed opportunities to identify HIV infection led to potentially preventable opportunistic infections, despite our current era of widely available, effective antiretroviral therapy.

Indexed as

aidsimmigrant healthneurologyopportunistic infectionpathology

Identifiers

PMID41938672
PMCPMC13049230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.