ReviewFrontiers in surgery2026
When to use a tourniquet in primary total knee arthroplasty? A systematic review and meta-analysis.
Review in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study aimed to investigate the optimal timing strategy for tourniquet use in primary total knee arthroplasty (TKA). Methods: A systematic search of PubMed, EMBASE, Web of Science, and the China National Knowledge Infrastructure was conducted to identify randomized controlled trials published up to January 2023. The included studies compared the use of a tourniquet solely during cementation (specific-duration tourniquet, SDT) vs. its use throughout the majority of the surgical procedure (majority-duration tourniquet, MDT). MDT was defined as tourniquet inflation prior to the surgical incision and deflation only after the cement had hardened. Continuous variables were pooled using the weighted mean difference (WMD), and relevant subgroups were analyzed independently. Results: Six studies involving 358 patients (386 knees) were included and assigned to either the SDT or MDT group. Meta-analysis showed that while the SDT group experienced higher intraoperative blood loss [WMD = -68.62, 95% confidence interval (CI): (-93.72 to -43.52), Conclusion: The SDT strategy may be associated with a reduced risk of postoperative complications and accelerated early functional recovery compared to the MDT strategy in primary TKA. Therefore, tourniquet application during SDT appears to be the optimal timing for primary TKA.
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