ArticleInternational journal of surgery case reports2026
A case report and literature review of pediatric multifocal melorheostosis in a unilateral limb.
Article in International journal of surgery case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Melorheostosis Involving the Carpal and Metacarpal Bones: Diagnostic Insights From Multimodal Imaging.Clinical case reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction and importance: Melorheostosis (Léri-Joanny syndrome) is a rare, nonhereditary, congenital sclerotic bone dysplasia with an estimated prevalence of 0.9 per million. Its enigmatic etiology and distinctive "melting wax" radiological appearance warrant detailed case reporting to enhance understanding of diagnosis and management, particularly in pediatric populations. Case presentation: A 9-year-old male presented with incidental right upper limb bone abnormalities discovered post-trauma. Asymptomatic without pain/swelling, he had no relevant family history. Laboratory tests (CBC, CRP, ESR) were normal. Imaging revealed unilateral cortical sclerosis with increased density in the right scapular coracoid process, humeral head, distal humerus, ulnar head, wrist, and metacarpals, exhibiting a pathognomonic "melting wax drip" pattern. Histopathology confirmed irregular endosteal bone proliferation, densely arranged lamellar bone, and enlarged/distorted Haversian canals . Clinical discussion: Melorheostosis predominantly affects limbs unilaterally; multifocal involvement (as here) is uncommon. Radiography remains the diagnostic cornerstone, supplemented by CT/MRI for spatial extent. This case was classified as endosteal subtype. Management is symptom-directed: asymptomatic cases require monitoring only. Surgical correction (e.g., osteotomy) is reserved for severe pain/deformity refractory to analgesics/physiotherapy. Long-term follow-up is critical due to theoretical malignant transformation concerns, though unreported clinically. Conclusion: This pediatric case underscores melorheostosis' incidental presentation and diagnostic reliance on classic imaging. The patient remained asymptomatic over 6 months, obviating intervention. Longitudinal surveillance is planned to elucidate natural history, contributing to management paradigms for this rare entity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.