Evidence map›Paper›PMID 41938395›Full record

ArticleInternational journal of surgery case reports2026

Impact of lidocaine-induced mydriasis on postoperative outcomes in deep sclerectomy: a case report.

Khalid A Aldihan, Dania Bamefleh, Nouf Alzendi, Ahmed K Alharthi

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In one paragraph

Article in International journal of surgery case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Khalid A AldihanGlaucoma Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0001-7767-6509
Dania BameflehGlaucoma Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Nouf AlzendiGlaucoma Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Ahmed K AlharthiFellowship and Residency Training Department, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Non-penetrating deep sclerectomy (NPDS), introduced in 1989, is a glaucoma surgery technique that reduces intraocular pressure (IOP) by removing a deep scleral flap to facilitate aqueous humor drainage. Lidocaine, a local anesthetic, blocks sodium channels to reduce pain. It also affects pupil size and accommodation, particularly in light-colored irises, though the exact mechanisms are not well understood. Importance: This report highlights the potential impact of lidocaine on pupil dynamics and its role in altering the functionality of surgically created outflow pathways. Case presentation: A 60-year-old woman with advanced normal tension glaucoma underwent bilateral deep sclerectomy. The right eye surgery was successful, but the left eye developed an acute rise in IOP following the use of topical lidocaine. The mydriatic effect led to bleb dysfunction and eventual surgical failure, necessitating conversion to trabeculectomy. Clinical discussion: The transient mydriatic effect of lidocaine can compromise aqueous humor dynamics during the early postoperative period of deep sclerectomy. In eyes with light-colored irises, this effect may be more pronounced, increasing the risk of failure and IOP spikes. This case highlights the need for ophthalmologists to consider alternative anesthetics and to closely monitor postoperative pupil dynamics to avoid compromising surgical outcomes. Conclusion: Lidocaine-induced mydriasis can adversely affect the results of a deep sclerectomy. Awareness of this potential complication and careful selection of anesthetic agents are crucial to optimize outcomes in glaucoma surgery.

Indexed as

deep sclerectomylidocainemydriasis

Identifiers

PMID41938395
PMCPMC13045948

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.