ArticleInternational journal of surgery case reports2026
Solitary extramedullary plasmacytoma of the tongue: a case report.
Article in International journal of surgery case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- When plasmacytoma defies expectations: An unusual maxillary presentation with mixed imaging features in a young patient.Radiology case reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction and Importance: Extramedullary plasmacytomas are rare solitary plasma cell neoplasms that occur outside the bone marrow. Primary tongue involvement is exceptionally uncommon and presents a significant diagnostic challenge. Their clinical presentation is often subtle and may closely mimic more common neoplastic processes. Case Presentation: We report the case of a 35-year-old man who presented with a gradually enlarging, firm, and painless mass on the ventral surface of the tongue that had been evolving for 5 months. Histopathological and immunohistochemical analyses revealed sheets of atypical plasma cells expressing CD38 and CD138 with kappa light-chain restriction, consistent with monoclonal plasma cell proliferation. A comprehensive systemic evaluation excluded multiple myeloma. The patient underwent definitive radiotherapy with a total dose of 50 Gy delivered in 25 fractions, resulting in complete remission without any functional impairment. At 9 months of follow-up, the patient showed no evidence of local recurrence or progression to multiple myeloma. Clinical Discussion: Primary extramedullary plasmacytoma of the tongue is exceptionally rare and may clinically mimic more common malignant or benign lesions, particularly in patients with a history of tobacco and alcohol exposure. An accurate diagnosis requires a multidisciplinary approach that integrates clinical findings, imaging, and histopathology, with immunohistochemical confirmation of monoclonality. Currently, radiotherapy remains the cornerstone of treatment, providing excellent local control and durable long-term remission. Conclusion: This case underscores the exceptional rarity of primary extramedullary plasmacytoma of the tongue and highlights the effectiveness of radiotherapy as a curative and function-sparing treatment option for this condition, while emphasizing the necessity of long-term and lifelong surveillance to detect potential late recurrence or progression to multiple myeloma.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.