ArticleAACE endocrinology and diabetes
Relation of Serum α-Amylase Level With Glycated Hemoglobin and Trace Elements in Patients With Diabetes Mellitus.
Article in AACE endocrinology and diabetes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Diabetes mellitus (DM) arises from insufficiencies in insulin secretion and action. The pancreatic α-amylase enzyme is involved in starch metabolism and influences glycated hemoglobin (HbA1c) level. The current study examines relationships between blood glucose level, α-amylase activity, HbA1c, and several trace elements (Cu, Zn, and Mg). Case description: Eighteen healthy control subjects and 31 patients with type 2 diabetes from both genders were recruited for this study. The enzymatic colorimetric method was used to assess serum glucose levels and α-amylase activity. The boronate affinity method and atomic absorption spectroscopy were used to measure HbA1c and trace elements, respectively. Discussion: In comparison to the control group, the diabetes groups' mean levels of α-amylase were slightly higher. The Cu level was significantly increased ( Conclusion: As the enzyme α-amylase correlated with HbA1c and glucose levels, it may serve as a supplementary marker of pancreatic exocrine involvement in patients with diabetes, but its predictive or diagnostic utility remains unproven. The pathophysiology of DM is complicated by altered trace element levels.
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