ArticleAnnals of pediatric cardiology
Cardiac magnetic resonance features of the left ventricle in d-transposition of the great arteries after arterial switch operation: Results from a single center.
Article in Annals of pediatric cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: This study aims to measure and describe left ventricular (LV) volumetric parameters, aortic regurgitation, and strain in patients who have undergone an arterial switch operation (ASO) for d-transposition of the great arteries (d-TGA), and to evaluate the incidence of abnormal cardiac magnetic resonance (CMR) findings in this cohort of patients. Materials and Methods: We retrospectively analyzed CMR in children and adults with repaired d-TGA, post-ASO, who underwent imaging in our center between 2011 and 2019 using the following sequences: Cine steady-state free precession, phase-contrast (PC) flows, and contrast angiograms on a 1.5T scanner. We measured the following parameters: indexed LV end-diastolic and end-systolic volumes, LV ejection fraction (LVEF), and aortic regurgitation fraction (AI%) using PC flows. Two-and 3-dimensional (2d and 3D) LV global radial, circumferential, and longitudinal strain were calculated using Circle cvi42. Results: Fifty-two studies were finally analyzed (male 33%, median age 14.3 years). Nine (17%) had reduced LVEF as measured by CMR. The incidence of late gadolinium enhancement is 9.6%. Among adult patients (for whom normative data are available for comparison), 2D and 3D global LV strain values were within the normal range. Conclusions: CMR characteristics of the left ventricle (including global 2D and 3D strain parameters) and the neo-aortic valve are reassuring late after arterial switch operation in the majority of patients with d-transposition of the great arteries. CMR is particularly useful to detect late gadolinium enhancement.
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