Evidence map›Paper›PMID 41938225›Full record

ArticleJAACAP open2026

The Kids FACE FEARS Pragmatic Randomized Trial of Therapist-Led vs Guided Internet Cognitive Behavioral Therapy for Pediatric Anxiety: Rationale and Methods.

Jonathan S Comer, Donna B Pincus, Molly C Adrian, Gary McCreary, Leslie Miller, Tomas Munarriz, Kathleen Myers, Karen Xiomara Pierre-Louis, Rheanna Platt, Melissa K Ripley and 27 more

Registry-linked trialAbstract read
In one paragraph

Article in JAACAP open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03707158 (Kids Formats of Anxiety Care Effectiveness Study For Extending the Acceptability and Reach of Services), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03707158 nacompletednot on this map

Kids Formats of Anxiety Care Effectiveness Study For Extending the Acceptability and Reach of Services (Kids FACE FEARS)

TypeinterventionalSponsorBoston Medical CenterRan2019 to 2024Enrolled305ConditionsChild Anxiety, Anxiety Disorders, Anxiety, Anxiety SymptomsArmsTherapist-Led CBT (telehealth, office-based, or hybrid), Guided Online CBT
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Jonathan S ComerFlorida International University, Miami, Florida.
Donna B PincusBoston University, Boston, Massachusetts.
Molly C AdrianUniversity of Washington, Seattle, Washington.
Gary McCrearyBoston University, Boston, Massachusetts.
Leslie MillerJohns Hopkins University School of Medicine, Baltimore, Maryland.
Tomas MunarrizSimmons University, Boston, Massachusetts.
Kathleen MyersUniversity of Washington, Seattle, Washington.
Karen Xiomara Pierre-LouisKids FACE FEARS Parent and Family Advisory Council, Chelsea, Massachusetts.
Rheanna PlattJohns Hopkins University School of Medicine, Baltimore, Maryland.
Melissa K RipleyKids FACE FEARS Parent and Family Advisory Council, Melrose, Massachusetts.
Andrea E SpencerAnn & Robert H. Lurie Children's Hospital of Chicago and the Feinberg School of Medicine-Northwestern University, Chicago, Illinois.
Haniya Saleem SyedaUniversity of California, Los Angeles, California.
Margarita AlegríaHarvard Medical School, Massachusetts General Hospital, Boston, Massachusetts.
Amelia BrandtJohns Hopkins University School of Medicine, Baltimore, Maryland.
Carolina CostaFlorida International University, Miami, Florida.
Lindsay CooperJohns Hopkins University School of Medicine, Baltimore, Maryland.
Stefany CoxeCedars-Sinai Medical Center, Los Angeles, California.
Annie W DantowitzInStride Health, Wellesley Hills, Massachusetts.
Anthony Steven DickFlorida International University, Miami, Florida.
Alyssa M FarleyBoston University, Boston, Massachusetts.
Jami M FurrFlorida International University, Miami, Florida.
Alex E KellerBoston Child Study Center, Boston, Massachusetts.
Julia A LejeuneUniversity of Illinois Chicago, Chicago, Illinois.
Lauren F McLellanMacquarie University, Sydney, Australia.
Dana L McMakinFlorida International University, Miami, Florida.
Rachel A MersonBoston University, Boston, Massachusetts.
Ricardo F MuñozPalo Alto University, Palo Alto, California.
Ronald M RapeeMacquarie University, Sydney, Australia.
Kendra L ReadUniversity of Washington, Seattle, Washington.
Sara Rivero-ConilNicklaus Children's Hospital, Miami, Florida.
Bridget PoznanskiBoston Medical Center, Chobanian & Avedisian School of Medicine, Boston University, Boston, Massachusetts.
Michelin Jane JanvierUniversity of Miami Miller School of Medicine, Miami, Florida.
Hanan N SalemUniversity of California, Santa Barbara, Santa Barbara, California.
Philip ShumwayUniversity of Tulsa, Tulsa, Oklahoma.
Jennifer SikovFlorida International University, Miami, Florida.
Michelle V PorcheUniversity of California Riverside School of Medicine, Riverside, California.
Lisa R FortunaUniversity of California Riverside School of Medicine, Riverside, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Pediatric anxiety constitutes a serious public health concern. Cognitive behavioral therapy (CBT) is a gold standard treatment, preferred by families over pharmacological options, but barriers limit CBT accessibility. Modern CBT formats include varying levels of therapist involvement and differential technologies to overcome barriers, but little is known about their effectiveness in typical care settings, as well as in pediatric care. The Kids Formats of Anxiety Care Effectiveness study For Extending the Acceptability and Reach of Services (Kids FACE FEARS) trial addresses these gaps. Method: The Kids FACE FEARS trial was a multisite, pragmatic randomized trial comparing therapist-led CBT (telehealth, office-based, or hybrid) with guided internet-based CBT (self-administered/self-paced, with minimal therapist support) for treating anxiety in youth (7-18 years old) identified in pediatric care. English- and Spanish-speaking families were enrolled from high-volume, urban pediatric health care sites affiliated with major medical centers in 4 metropolitan regions. This article describes the study's rationale, treatment conditions, participant recruitment, assessment schedule/strategy, and provider training/consultation. Discussion: Recent innovations have expanded CBT delivery options for pediatric anxiety. This is the first multisite randomized trial directly comparing CBT formats that draw on differential levels of therapist involvement and modes of technology. Sampling and study design features poise the Kids FACE FEARS trial to be one of the largest and most diverse/representative controlled trials of CBT for pediatric anxiety. In the context of evolving CBT delivery options, trial findings can inform patient-centered decision making and help tailor treatment selections for underserved youth with anxiety. Clinical trial registration information: Kids FACE FEARS Comparative Effectiveness Research; https://clinicaltrials.gov/study/NCT03707158.

Indexed as

anxietycognitive behavioral therapyguided iCBTiCBTtelehealth

Identifiers

PMID41938225
PMCPMC13043486

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.