Evidence map›Paper›PMID 41938139›Full record

ArticleMaterials today. Bio2026

Synergistic osteogenesis, angiogenesis, and immune reprogramming by a metal-phenolic functionalized electrospun fibrous membrane for alveolar bone regeneration.

Jia Zhou, Yue Hu, Jiali Bao, Shiyuan Yang, Yan Zhu, Zixiao Zhang, Minxi Chen, Yuning Zhou, Kaili Lin, Yuanjin Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jia ZhouDepartment of Oral Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Huangpu District, Shanghai, China.
Yue HuDepartment of Oral Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Huangpu District, Shanghai, China.
Jiali BaoDepartment of Oral Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Huangpu District, Shanghai, China.
Shiyuan YangDepartment of Oral Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Huangpu District, Shanghai, China.
Yan ZhuDepartment of Oral Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Huangpu District, Shanghai, China.
Zixiao ZhangDepartment of Oral Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Huangpu District, Shanghai, China.
Minxi ChenDepartment of Oral Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Huangpu District, Shanghai, China.
Yuning ZhouDepartment of Oral Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Huangpu District, Shanghai, China.
Kaili LinCollege of Stomatology, Shanghai Jiao Tong University, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Huangpu District, Shanghai, China.
Yuanjin XuDepartment of Oral Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Huangpu District, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alveolar bone defects, whether caused by pathology or trauma, severely compromise oral function and facial aesthetics. However, current commercial guided bone regeneration (GBR) membranes exhibit limitations in mechanical properties, degradation rate matching, and osteogenic activity. In response to these challenges, this study developed a multifunctional bioactive electrospun fibrous membrane (EFM) composed of silk fibroin and polycaprolactone and loaded with curcumin-strontium nanoparticles (Cur-Sr/SF/PCL). This membrane demonstrates superior mechanical strength, suitable degradation behavior, and effective barrier function against soft tissue infiltration. Crucially, the synergistic release of curcumin and Sr

Indexed as

Alveolar bone regenerationCurcuminElectrospinningMetal-phenolic nanoparticlesOsteogenesis

Identifiers

PMID41938139
PMCPMC13049611

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.