ArticleReproductive medicine and biology
Impact of Inner Cell Mass Hatching Levels Before Vitrification on Clinical Pregnancy in Preimplantation Genetic Testing for Euploidy Cycles.
Article in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
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Abstract
Purpose: Does an association exist between the ICM/TE hatching levels of biopsied blastocysts before vitrification and implantation? Methods: Total 541 single blastocyst transfers in PGT-A cycles were collected. The degree of TE/ICM extrusion from the zona pellucida before vitrification was categorized as (1) ICM hatching level ≤ 50% and > 50%, (2) TE hatching level ≤ 25% and > 25%. Results: TE hatching levels were not associated with clinical pregnancy probability ( Conclusion: Blastocysts with an ICM hatching level of > 50% had the lower implantation potential, which may be related to the increased incidence of ICM cell apoptosis.
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