Evidence map›Paper›PMID 41937789›Full record

ReviewFrontiers in plant science2026

Research progress and applications of gene activation editing technology in crops.

Jing Lv, Xinxi He, Qi Wu, Yuhe Sun, Wenxuan Pu, Changbo Dai

Abstract readReview
In one paragraph

Review in Frontiers in plant science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jing LvTobacco Research Institute, Chinese Academy of Agricultural Sciences, Qingdao, China.
Xinxi HeTechnology Center, China Tobacco Hunan Industrial Co., Ltd., Changsha, China.
Qi WuTobacco Research Institute, Chinese Academy of Agricultural Sciences, Qingdao, China.
Yuhe SunTobacco Research Institute, Chinese Academy of Agricultural Sciences, Qingdao, China.
Wenxuan PuTechnology Center, China Tobacco Hunan Industrial Co., Ltd., Changsha, China.
Changbo DaiTobacco Research Institute, Chinese Academy of Agricultural Sciences, Qingdao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, CRISPR/Cas gene editing technology has become a fundamental method in biological breeding. As a vital tool for overcoming technological obstacles, it is currently widely used in functional gene research and genetic enhancement across a variety of organisms. Currently, CRISPR activation (CRISPRa) technology based on dCas9 fusion transcription activation domains has emerged as a powerful tool for expanding the application of CRISPR/Cas systems in improving traits in plants, animals, and microorganisms. This overview starts by going over the underlying principles and components of gene activation editing technology, as well as the phases of development of its three generations. It summarises the present difficulties and potential directions in this field while concentrating on the use of gene activation editing in important crop traits including growth and development regulation, stress resistance, and quality regulation. The objective is to offer valuable insights for the research and development of crop breeding.

Indexed as

CRISPR/Cascrop breedingcrop improvementfunctional genomicsgene activation

Identifiers

PMID41937789
PMCPMC13047105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.