Evidence map›Paper›PMID 41937760›Full record

ArticleFrontiers in plant science2026

Glutamine alleviates the toxicity of externally applied amino acids in Arabidopsis.

Lauren M Kerwien, Rayah Edelson, Kristupas Vorobjovas, Guillaume Pilot

Abstract read
In one paragraph

Article in Frontiers in plant science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lauren M Kerwien *School of Plant and Environmental Sciences, Virginia Tech, Blacksburg, VA, United States.
Rayah Edelson *School of Plant and Environmental Sciences, Virginia Tech, Blacksburg, VA, United States.
Kristupas VorobjovasSchool of Plant and Environmental Sciences, Virginia Tech, Blacksburg, VA, United States.
Guillaume PilotSchool of Plant and Environmental Sciences, Virginia Tech, Blacksburg, VA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Plants use amino acids not only as building blocks for protein synthesis, but also as nitrogen carriers between the various organs and as precursors of a plethora of specialized compounds that fulfill essential functions ranging from structural roles to interaction with other organisms. Feedback regulation of amino acid metabolic enzymes is well studied in plants and has been accepted as a main regulatory mechanism of pathway activity. Studies in Results and discussion: The present study established an Arabidopsis-based framework to further study the mechanisms controlling the activity of amino acid metabolic pathways. In this context, we determined with precision the toxicity of each amino acid on Arabidopsis plants grown in solid and liquid media. The level of toxicity varied between 0.3 and 4 mM, depending on the amino acid, with some amino acids found non-toxic at concentrations up to 20 mmol.l

Indexed as

amino acid metabolismamino acid transportammoniumbranched chain amino acidsnitrateregulation - physiologicalTarget of Rapamycin (TOR)

Identifiers

PMID41937760
PMCPMC13044093

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.