Evidence map›Paper›PMID 41937296›Full record

ArticleSubstance use & misuse2026

Sexualized Drug Use Linked to Higher HIV Testing Frequency Among Men Who Have Sex with Men in Three Chinese Cities with High HIV Prevalence.

Danyang Luo, Sainan Wang, Xiuping Zhao, Zhizheng Huang, Xuejiao Hu, Cong Liu, Zhen Dai, Haipeng Zha, Pan Gao, Jun Wang and 8 more

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In one paragraph

Article in Substance use & misuse, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

18 authors.

Danyang LuoDepartment of Behavioral, Social, and Health Education Sciences, Emory University, Atlanta, Georgia, USA.
Sainan WangDepartment of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
Xiuping ZhaoSuzhou Center for Disease Control and Prevention, Suzhou, Jiangsu, China.
Zhizheng HuangSuzhou Center for Disease Control and Prevention, Suzhou, Jiangsu, China.
Xuejiao HuWuhan Center for Disease Control and Prevention, Wuhan, Hubei, China.
Cong LiuWuhan Center for Disease Control and Prevention, Wuhan, Hubei, China.
Zhen DaiChengdu Center for Disease Control and Prevention, Chengdu, Sichuan, China.
Haipeng ZhaChengdu Tongle Health Consulting Service Center, Chengdu, Sichuan, China.
Pan GaoYouth Public Health Service Center, Hefei, Anhui, China.
Jun WangDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
Yehuan SunDepartment of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
Shufang SunDepartment of Behavioral and Social Sciences, Brown University School of Public Health, Providence, Rhode Island, USA.
Cui YangDepartment of Health Behavior, Society, and Policy, Rutgers School of Public Health, New Jersey, USA.
M Kumi SmithDivision of Epidemiology & Community Health, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.
Melvin D LivingstonDepartment of Behavioral, Social, and Health Education Sciences, Emory University, Atlanta, Georgia, USA.
Don OperarioDepartment of Behavioral, Social, and Health Education Sciences, Emory University, Atlanta, Georgia, USA.
Hongbo ZhangDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
Zhihua ZhangDepartment of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China.

Funding

Mobile Health Intervention to Increase HIV Self Testing and Linkage to Services for High-Risk Men in ChinaR01MH123352 · NIMH · EMORY UNIVERSITY · PI OPERARIO, DON, YANG, CUI · 2020 to 2024
$2.8M
NIMH NIH HHS R01 MH123352
6 · The paper itself

Abstract

backgroundMen who have sex with men (MSM) in China experience high HIV prevalence, yet little is known about the HIV testing behaviors of MSM among those who engage in sexualized drug use (SDU). Clarifying these patterns is essential for designing targeted HIV prevention interventions.

methodsWe analyzed baseline survey data from 1,800 MSM recruited in Chengdu, Suzhou, and Wuhan (2021-2022). Participants reported HIV testing history and SDU, including alcohol, rush/poppers, amphetamines, and other drugs (ketamine, marijuana, heroin, Ma Gu). Logistic regression estimated associations between SDU and HIV testing within 6 months, adjusting for demographics.

resultsThe mean age was 31.1 years; nearly half held a bachelor's degree or higher. Alcohol (68%) and rush/poppers (43%) were the most common substances used before or during sex, while amphetamines (1.8%) and other drugs (1.7%) were rarely used. Any drug use excluding alcohol was positively associated with recent HIV testing (adjusted OR = 1.35; 95% CI: 1.08-1.68). Rush/poppers use specifically was linked to higher odds of testing (adjusted OR = 1.32; 95% CI: 1.05-1.63).

conclusionsSDU-particularly rush/poppers use-is prevalent among Chinese MSM and associated with greater HIV testing uptake. Tailored interventions that integrate substance use counseling with HIV testing promotion may help sustain high testing uptake and reduce transmission risk.

Indexed as

HIV InfectionsHIV TestingHomosexuality, MaleSubstance-Related DisordersAdolescentAdultChemsexChinaHumansMalePrevalenceYoung AdultChinaHIV/STIMSMsexualized drug use

Identifiers

PMID41937296
PMCPMC13128678

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