Trial reportJournal of neuroengineering and rehabilitation2026
The impact of robot-assisted training on gait, balance, and endurance in patients with partial spinal cord injuries: insights from rehabilitation.
Trial report in Journal of neuroengineering and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Robotic-Assisted Rehabilitation and Spinal Neuromodulation After Spinal Cord Injury: From Mechanisms to Trial-Informed Practice.Journal of clinical medicine · 2026Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study evaluated the effectiveness of robotic-assisted gait training in improving gait function, balance, and endurance in individuals with chronic spinal cord injury (SCI). It compared robotic-assisted therapy with conventional rehabilitation and examined the impact of training frequency.
methodsA randomized controlled trial was conducted at specialized SCI rehabilitation centers. Seventy-five participants aged 19–40 with chronic partial SCI American Spinal Injury Association Impairment Scale (AIS) grades B, C, or D were enrolled in this randomized controlled trial. A pre-registered athletic subgroup consisting of 45 individuals with intensive competitive sports backgrounds (≥ 4 sessions/week pre-injury) was designated for subgroup analysis. The remaining 30 participants were physically active non-athletes (2–3 sessions/week pre-injury). Participants were divided into three groups: L1 (robotic-assisted gait training once weekly), L2 (robotic-assisted gait training twice weekly), and C (conventional rehabilitation). Functional outcomes were assessed using the 10-Meter Walk Test (10MWT), 6-Minute Walk Test (6MWT), Walking Index for Spinal Cord Injury II (WISCI II), Lower Extremity Motor Score (LEMS), Timed Up and Go Test (TUG), and stabilometry before and after the intervention.
resultsThe L2 group demonstrated the greatest improvements: TUG time decreased by 7.7 ± 3.0 s (17.2 ± 2.5 s PRE vs. 9.5 ± 1.8 s POST; −44.8%, η² = 0.18), and 6MWT distance increased by 43.5 ± 16.2 m (35.5 ± 4.8 m PRE vs. 79 ± 14 m POST; +122.5%, η² = 0.25). These absolute improvements substantially exceed established MCID thresholds and were accompanied by clinically meaningful gains in quality of life. Robotic-assisted therapy, particularly at higher training frequencies, significantly outperformed conventional rehabilitation, especially in AIS D patients.
conclusionsRobotic-assisted gait training effectively improves gait function, endurance, and balance, with enhanced benefits observed at higher training frequencies. Higher training frequency demonstrated clinically meaningful improvements across all participants. While improvements were observed across the cohort, future adequately powered trials are needed to systematically investigate whether athlete-specific training histories influence responsiveness to different Lokomat frequencies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.