Evidence map›Paper›PMID 41936688›Full record

ArticleScientific reports2026

Marginal causal effect of fungicide seed treatments on soybean yield and uncertain profitability in the US Midwest.

Paul D Esker, Denis A Shah, Spyridon Mourtzinis, Patricio Grassini, Tatiane Severo Silva, Shawn P Conley

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paul D EskerDepartment of Plant Pathology and Environmental Microbiology, Pennsylvania State University, 211 Buckhout Lab, University Park, PA, 16802, USA. pde6@psu.edu.
Denis A ShahDepartment of Plant Pathology, Kansas State University, 4024 Throckmorton Plant Sciences Center, 1712 Claflin Road, Manhattan, KS, 66506, USA.
Spyridon MourtzinisDepartment of Plant and Agroecosystem Sciences, University of Wisconsin-Madison, Moore Hall, 1575 Linden Drive, Madison, WI, 53705, USA.
Patricio GrassiniDepartment of Agronomy and Horticulture, University of Nebraska-Lincoln, 1825 N 38th St., 202 Keim Hall, Lincoln, NE, 68583-0915, USA.
Tatiane Severo SilvaDepartment of Plant and Agroecosystem Sciences, University of Wisconsin-Madison, Moore Hall, 1575 Linden Drive, Madison, WI, 53705, USA.
Shawn P ConleyDepartment of Plant and Agroecosystem Sciences, University of Wisconsin-Madison, Moore Hall, 1575 Linden Drive, Madison, WI, 53705, USA.

Funding

North Central Soybean Research Program Project 204331United Soybean Board Project 24-210-S-A-1-A / 2411-210-0101USDA National Institute of Food and Agriculture Project PEN04836
6 · The paper itself

Abstract

Fungicide seed treatments (FSTs) are widely used in Midwest soybean production due to perceived disease risk. While some studies report significant yield increases, overall economic and environmental benefits remain unclear. This study utilized randomized controlled trial (RCT) and observational data to estimate the causal FST effect on soybean yield. Analysis of the RCT data revealed a modest average yield increase of 22.2 kg/ha attributable to FST. Observational data also indicated a small average yield gain of approximately 36 kg/ha. Monte Carlo simulations showed that yield gains often do not offset the seed treatment costs, with financial benefit likely only under low FST costs and high soybean prices. Given the limited economic return and concerns about the potential negative impacts of widespread FST use on soil microbes and non-target organisms, our research suggests that FSTs may not be necessary in Midwest soybean production, and growers should carefully evaluate their use based on individual farm gate economics as well as ecological considerations.

Indexed as

Fungicides, IndustrialGlycine maxSeedsMidwestern United StatesMonte Carlo MethodFungicides, IndustrialCausal effectsFungicide seed treatmentProfitabilitySoybeanUS Midwest

Identifiers

PMID41936688
PMCPMC13213029

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.