Evidence map›Paper›PMID 41936569›Full record

ArticleThe Medical journal of Australia2026

Reflex Testing for Hepatitis D Infection: A Unique Opportunity to Reduce Hepatitis D-Related Chronic Liver Disease Deaths in Australia.

Jessica Howell, Lauren Andersson, Miriam T Levy, James O'Beirne, Leon Adams, Katharine Irvine, Avik Majumdar, Golo Ahlenstiel, Kathy Jackson, Krispin Hajkowicz and 5 more

Abstract read
In one paragraph

Article in The Medical journal of Australia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jessica HowellSt Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.
Lauren AnderssonSt Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.
Miriam T LevyLiverpool Hospital Sydney, Sydney, New South Wales, Australia.ORCID 0000-0001-9329-8018
James O'BeirneSunshine Coast University Hospital, Sunshine Coast, Queensland, Australia.
Leon AdamsUniversity of Western Australia, Perth, Western Australia, Australia.
Katharine IrvineUniversity of Queensland, Brisbane, Queensland, Australia.
Avik MajumdarAW Morrow Gastroenterology and Liver Centre, Royal Prince Albert Hospital, Sydney, New South Wales, Australia.
Golo AhlenstielWestern Sydney University, Sydney, New South Wales, Australia.
Kathy JacksonVictorian Infectious Diseases Reference Laboratory, Doherty Institute, Melbourne, Victoria, Australia.
Krispin HajkowiczUniversity of Queensland, Brisbane, Queensland, Australia.
Joseph DoyleBurnet Institute, Melbourne, Victoria, Australia.
Jane DaviesMenzies School of Health Research, Darwin, Northern Territory, Australia.ORCID 0000-0002-3843-837X
Sarah CherianSullivan Nicolaides Pathology, Brisbane, Queensland, Australia.
Wayne DimechNational Research Laboratory, Melbourne, Victoria, Australia.
Alexander J ThompsonSt Vincent's Hospital Melbourne, Melbourne, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic hepatitis D virus (HDV) infection always occurs as a coinfection with hepatitis B virus (HBV) and is the most severe form of viral hepatitis, associated with a high risk of cirrhosis, liver cancer and death. Effective treatment is now available for HDV-HBV coinfection and HDV screening is recommended for all people living with HBV, yet most people in Australia with HDV-HBV are diagnosed too late to prevent complications. This article calls for an urgent change in HDV testing policy and funding to implement reflex HDV antibody (anti-HDV) testing for all people diagnosed with HBV infection, thus enabling timely diagnosis of HDV-HBV coinfection and rapid access to life-saving treatment.

Indexed as

Hepatitis B, ChronicHepatitis D, ChronicAustraliaCoinfectionHepatitis Delta VirusHumansLiver CirrhosisMass Screeningclinical pathologyhepatitis Bhepatocellular carcinomaliver cirrhosisliver diseasesviral hepatitis

Identifiers

PMID41936569
PMCPMC13050674

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.