ArticlePediatric dermatology
Erdafitinib-Induced Flexural Calcinosis Cutis in a Pediatric Patient: A Drug-Specific Side-Effect?
Article in Pediatric dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fibroblast growth factor receptor (FGFR) inhibitors are effective in malignancies with FGFR pathway alterations but may disrupt calcium-phosphate metabolism, leading to dermatologic side effects. We report a case of calcinosis cutis presenting as painful flexural plaques in a 16-year-old patient treated with erdafitinib for high-grade glioma. The patient's age, unusual lesion distribution, and spontaneous resolution after drug discontinuation highlight a previously unreported association in pediatrics. Recognizing this potential adverse effect may help avoid unnecessary diagnostic or therapeutic interventions.
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Registered trials
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