Evidence map›Paper›PMID 41935972›Full record

ArticleLasers in surgery and medicine2026

Fractional CO

Qiao Li, Jian Meng, Yajing Wang, Yueyue Chen, Xiaoyu Niu, Dongmei Wei

Abstract read
In one paragraph

Article in Lasers in surgery and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qiao LiDepartment of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Jian MengDepartment of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Yajing WangDepartment of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.ORCID https://orcid.org/0000-0002-1326-1459
Yueyue ChenDepartment of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Xiaoyu NiuDepartment of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Dongmei WeiDepartment of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.ORCID https://orcid.org/0000-0001-6922-0296

Funding

Key Research Projects of Sichuan Science and Technology Department 2023NSFSC1606Key Research Projects of Sichuan Science and Technology Department 2023YFG0128Key Research Projects of Sichuan Science and Technology Department 23ZDYF2049National Key Research and Development Program of China 2021YFC2009100Research Projects of Sichuan Science and Technology Department 2023YFQ0070Research Projects of Sichuan Science and Technology Department 2023YFS0024Science & Technology Department of Sichuan Province 2019YFS0008Sichuan Provincial Health Commission Project 21ZD002Sichuan University 21H0103
6 · The paper itself

Abstract

backgroundVaginal relaxation syndrome (VRS) is a common condition that adversely affects women's quality of life. Conventional non-surgical therapies provide limited benefit for patients with mild to moderate disease. Fractional CO

objectiveTo prospectively evaluate the efficacy and safety of FxCO

methodsThis prospective self-controlled study enrolled 101 women diagnosed with mild to moderate VRS. All participants underwent three sessions of FxCO

resultsAll primary outcome measures improved following treatment. The mean FSFI total score increased from 21.4 to 25.9, the VLQ score improved from 2.68 to approximately 3.0, and the VHI score increased from 17.0 to 19.25 (all p < 0.001). Subgroup analyses indicated that treatment efficacy was not significantly influenced by parity, age, or the presence of concomitant urinary incontinence. Only mild and transient adverse events were reported, all of which resolved spontaneously.

conclusionsFxCO

Indexed as

Lasers, GasSexual Dysfunction, PhysiologicalVaginal DiseasesAdultFemaleFollow-Up StudiesHumansMiddle AgedProspective StudiesSyndromeTreatment OutcomeVaginafractional CO2 laserprospective studysafetysexual functiontreatment efficacyvaginal relaxation syndrome

Identifiers

PMID41935972
PMCPMC13269857

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.