Evidence map›Paper›PMID 41935202›Full record

ArticleCommunications biology2026

Asymmetry and redundancy of STAT5 paralogs across CD8

Svetlana Ristin, Molly Dalzell, Christopher Armstrong, Nisa Ilsin, Antonio M Fontanella, Luis Nivelo, Lothar Hennighausen, John J O'Shea, Alejandro V Villarino

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Svetlana Ristin *Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, USA.
Molly Dalzell *Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, USA.
Christopher ArmstrongDepartment of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, USA.ORCID http://orcid.org/0000-0002-9236-472X
Nisa IlsinDepartment of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, USA.
Antonio M FontanellaDepartment of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, USA.ORCID http://orcid.org/0000-0003-2178-0870
Luis NiveloDepartment of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, USA.
Lothar HennighausenNational Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
John J O'SheaLymphocyte Cell Biology Section, Molecular Immunology and Inflammation Branch, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA.
Alejandro V VillarinoDepartment of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, USA. alejandro.villarino@miami.edu.ORCID http://orcid.org/0000-0001-8068-2176

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fostering STAT5 signaling is key to immunotherapies that leverage CD8

Indexed as

CD8-Positive T-LymphocytesCell DifferentiationSTAT5 Transcription FactorTumor Suppressor ProteinsAnimalsMiceMice, Inbred C57BLSignal TransductionStat5a protein, mouseStat5b protein, mouseSTAT5 Transcription FactorTumor Suppressor Proteins

Identifiers

PMID41935202
PMCPMC13083952

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.