ArticleTranslational psychiatry2026
Momentary anxiety and autonomic responses during everyday social interactions among patients with depression.
Article in Translational psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Cardiac autonomic dysfunction is associated with advanced stage, fast progression and poor survival in amyotrophic lateral sclerosis.Journal of neuromuscular diseases · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Social interactions play a central role in regulating affect and physiological arousal, with familiar and supportive relationships often associated with reduced anxiety and adaptive autonomic responses. However, it remains unclear whether individuals with depression benefit similarly from these so-called social buffering effects in everyday life. The present study examined momentary anxiety and cardiovascular responses (heart rate [HR] and heart rate variability [HRV]) during real-life social interactions in patients suffering from depression (N = 57) and matched healthy controls (N = 57). Participants reported on the familiarity and the gender of social interaction partners and the interaction context across five days, while a subsample also wore ambulatory electrocardiogram sensors. Across the patient and control group, higher interaction partner familiarity was associated with reduced state anxiety. However, only controls reported lower social interaction anxiety with increasing familiarity, whereas this pattern was not observed in patients. State social interaction anxiety was higher in controls when they interacted with female interaction partners, while there were no differences for patients. Regarding autonomic responses, patients exhibited higher baseline and state HR and lower baseline and state HRV compared to controls, consistent with autonomic dysregulation. We also observed lower HRs in opposite-gender interactions among controls but not among patients. Overall, these findings suggest that familiar social interactions are associated with lower levels of general state anxiety in both patients with depression and healthy controls, whereas social interaction anxiety and autonomic responses appear to show weaker associations with familiarity or the gender of interaction partners in patients. This research offers insights into how everyday social environments might support emotion regulation in clinical populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.