Plasma proteome profiling identifies novel biomarkers and predictors for schizophrenia.

Songyu Wu, Xinru Guo, Tingyi Jia, Zhouyang Sun, Ge Yu, Yixin Ouyang, Changgui Kou, Wei Bai

Abstract read

In one paragraph

Article in Translational psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Songyu WuDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, No. 1163 Xinmin Street, Changchun, 130021, China.

Xinru GuoDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, No. 1163 Xinmin Street, Changchun, 130021, China.

Tingyi JiaDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, No. 1163 Xinmin Street, Changchun, 130021, China.

Zhouyang SunDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, No. 1163 Xinmin Street, Changchun, 130021, China.

Ge YuDepartment of Social Medicine and Health Management, School of Public Health, Jilin University, No. 1163 Xinmin Street, Changchun, 130021, China.

Yixin OuyangDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, No. 1163 Xinmin Street, Changchun, 130021, China.

Changgui Kou *Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, No. 1163 Xinmin Street, Changchun, 130021, China. koucg@jlu.edu.cn.

Wei Bai *Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, No. 1163 Xinmin Street, Changchun, 130021, China. baiweijlu@jlu.edu.cn.ORCID http://orcid.org/0000-0001-9579-9959

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82073644

6 · The paper itself

Abstract

This study performed a systematic investigation through proteomic and longitudinal follow-up data from the UK Biobank (comprising 70 schizophrenia cases and 36,135 healthy controls) to reveal the association between protein biomarkers and the onset of schizophrenia in order to provide insights into the pathogenesis of schizophrenia. Cox regressions recognized 31 significant schizophrenia related proteins (P < 1.712 × 10

Indexed as

ProteomeSchizophreniaAdultBiomarkersCase-Control StudiesCell Adhesion MoleculesFemaleHumansLongitudinal StudiesMaleMendelian Randomization AnalysisProportional Hazards ModelsProteomicsUK BiobankBiomarkersCell Adhesion MoleculesProteome

Identifiers

PMID41935040

DOI10.1038/s41398-026-04017-2

PMCPMC13183922

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.