ArticleClinics (Sao Paulo, Brazil)2026
A novel machine learning model of smartphone-based 1-minute sit-to-stand test for prediction of six-minute walk test distance in patients with COPD.
Article in Clinics (Sao Paulo, Brazil), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundRegular assessment of exercise tolerance is essential for managing COPD, nevertheless, the standard 6-Minute Walk Test (6MWT) is difficult to perform outside clinical settings. This study aimed to develop and validate a smartphone-based digital 1-Minute Sit-to-Stand Test (1MSTST) to estimate 6-Minute Walking Distance (6MWD) by integrating data from the phone's Inertial Motion Unit (IMU) with advanced machine learning algorithms, offering a convenient alternative for remote functional assessment.
methodsThe enrolled COPD patients completed the smartphone-based digital 1MSTST and 6MWT with a minimum 15-minute rest period between the two tests. Accelerometer and gyroscope data were recorded by a smartphone throughout the 1MSTST. Systolic and Diastolic Blood Pressure (SBP, DBP), Heart Rate (HR) and Pulse Oxygen Saturation (SpO
resultsA total of 66 patients with stable COPD were enrolled to build the predictive model for 6MWD. The change of HR and SBP after 1MSTST was higher than that of 6MWT (paired t-test, ΔHR: p < 0.0001, ΔSBP: p < 0.0001) with no significant difference in the change of DBP and SpO
conclusionsThe smartphone-based digital 1MSTST, combined with machine learning, can accurately estimate 6MWD. The significance of this study lies in proposing a novel assessment paradigm that may serve as a practical tool for remote monitoring of exercise capacity in COPD management.
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