Evidence map›Paper›PMID 41934540›Full record

ArticleJournal of neuro-oncology2026

Significance of shunt placement for secondary communicating hydrocephalus in patients with high-grade glioma.

Koji Saito, Daisuke Kawauchi, Yohei Ono, Makoto Ohno, Shunsuke Yanagisawa, Takaki Omura, Takuma Aoki, Genta Fujii, Yoshitaka Narita

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In one paragraph

Article in Journal of neuro-oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Koji SaitoDepartment of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Daisuke KawauchiDepartment of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan. dakawau2@ncc.go.jp.ORCID http://orcid.org/0000-0002-7679-173X
Yohei OnoDivision of Biostatistics and Bioinformatics, School of Public Health, St. Luke's International University, Tokyo, Japan.
Makoto OhnoDepartment of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Shunsuke YanagisawaDepartment of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Takaki OmuraDepartment of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Takuma AokiDepartment of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Genta FujiiDepartment of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Yoshitaka NaritaDepartment of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHydrocephalus is a common complication of high-grade glioma (HGG). However, the indications for and prognostic impact of shunt placement remain unclear. We aimed to assess the shunt placement effectiveness and safety for hydrocephalus in patients with HGG and identify clinical factors associated with neurological and survival outcomes.

methodsWe retrospectively identified HGG patients with communicating hydrocephalus (CH) treated at our hospital between October 2010 and December 2024. Patient characteristics, changes in Karnofsky Performance Status (KPS) before and after shunt placement, and survival were analyzed in these patients.

resultsDuring the study period, 31 HGG patients underwent shunt placement for CH. For the patients, positive lumbar tap test results and a shorter duration from KPS decline to shunt placement were significantly associated with greater KPS improvement in analyses (p = 0.034 and 0.043). No patients showed KPS improvement when shunt placement was performed more than three months after KPS decline. For the patients who experienced an improved KPS score after shunt surgery, the median postshunting survival was 20.0 months. Postsurgical infection was observed in two cases (6.4%), and shunt revision surgery was required in three cases (9.6%).

conclusionsShunt placement may be considered in selected patients with HGG and CH, particularly those with a positive lumbar tap test and a short interval from KPS decline.

Indexed as

Brain NeoplasmsCerebrospinal Fluid ShuntsGliomaHydrocephalusAdultAgedFemaleFollow-Up StudiesHumansKarnofsky Performance StatusMaleMiddle AgedPrognosisRetrospective StudiesGliomaHydrocephalusLumbar tap testShunt placement

Identifiers

PMID41934540

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.