ArticleSurgical and radiologic anatomy : SRA2026
Microsurgical anatomy of the corpus callosum: a fiber microdissection, tractography and illustrative study.
Article in Surgical and radiologic anatomy : SRA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe corpus callosum (CC) is the largest commissural white matter structure in the human brain, responsible for interhemispheric communication. Despite its clinical significance in neurosurgical procedures, detailed anatomical studies of its fiber organization remain limited. The aim of this study was to investigate the fiber architecture and topography of the CC through combined microsurgical dissection, tractography, and illustrative analysis.
methodsTen formalin-fixed adult human brains (20 hemispheres) were prepared using Klingler’s method. Fiber dissections were performed under an operating microscope in medial-to-lateral, superior-to-inferior, and lateral-to-medial orientations. High-resolution diffusion data from the Human Connectome Project were used for tractographic validation via DSI Studio. The findings were further supported by schematic illustrations.
resultsDissection revealed a three-layered organization of callosal fibers: dorsal, intermediate, and ventral layers. Dorsal fibers connected homotopic cortical areas, particularly the motor and premotor cortices. Intermediate fibers projected toward the corona radiata and internal capsule. Ventral fibers included tapetal connections and fibers linking subcortical structures such as the caudate nuclei. Additionally, we identified accessory callosal bundles and cingular-splenial fibers, which have seldom been emphasized in the previous literature. Tractographic results confirmed the trajectories and lamination patterns observed during dissection.
conclusionOur integrative analysis provides a comprehensive educational depiction of corpus callosum lamination and topography. These findings should enhance anatomical understanding and inform neurosurgical approaches, particularly in callosotomy and transcallosal tumor surgery. Further studies are needed to explore the functional and clinical implications of these anatomical subdivisions.
Indexed as
Identifiers
41934516What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.